Results 51 to 60 of about 75,778 (296)

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source

A Computational Fluid Dynamics Study on Shearing Mechanisms in Thermal Elastohydrodynamic Line Contacts

Lubricants, 2019
A computational fluid dynamics (CFD) model of the thermal elastohydrodynamically lubricated (EHL) line contact problem has been developed for the purpose of exploring the physical processes that occur inside a thin EHL film subjected to shearing motion ...
Marko Tošić, Roland Larsson, Janko Jovanović, Thomas Lohner, Marcus Björling, Karsten Stahl   +5 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Radiation‐Resistant Aluminum Alloy for Space Missions in the Extreme Environment of the Solar System

Advanced Materials, EarlyView.
A novel ultrafine‐grained aluminum crossover alloy exhibits unprecedented radiation resistance and mechanical stability under extreme irradiation doses up to 100 dpa. The exceptional resilience arises from thermodynamically stable T‐phase precipitates, enabling lightweight structural materials for next‐generation spacecraft and extraterrestrial ...
Patrick D. Willenshofer, Matheus A. Tunes, Hi T. Vo, Lukas Stemper, Markus Alfreider, Oliver Renk, Graeme Greaves, Daniel Kiener, Peter J. Uggowitzer, Stefan Pogatscher   +9 more
wiley   +1 more source

Corrigendum: Implications of COVID-19 Vaccine Hesitancy: Results of Online Bulletin Board Interviews

Frontiers in Public Health, 2022
Jack M. Gorman, Sara E. Gorman, William Sandy, Nellie Gregorian, David A. Scales, David A. Scales   +5 more
doaj   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Study on Low-Frequency Repetitive Transcranial Magnetic Stimulation Improves Speech Function and Mechanism in Patients With Non-fluent Aphasia After Stroke [PDF]

, 2022
Guangtao Bai, Liang Jiang, Sai Huan, Pingping Meng, Yuyang Wang, Xiaona Pan, Shuai Yin, Yuyang Zhao, Qiang Wang   +8 more
openalex   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Numerical Analysis of Separation and Stream tube Dimensions in the Intakes Installed to Rectangular and Trapezoidal Channels

علوم آب و خاک, 2018
The study of flow patterns in front of intake has been attracted the attention of researchers during the past decades to explore the mechanism of flow and sediment entry to the intake.
S. M. Seyedian, M. Karami Moghadam, Y. Ramezani   +2 more
doaj  

Flow simulation in a flip bucket spillway: Dakpokei reservoir case study

Tạp chí Khoa học và Công nghệ
Simulating the hydraulic behavior of an ogee spillway with a free jet energy dissipation form is a complex task due to the involvement of two phases: liquid (water) and gas (air).
Vu Huy Cong
doaj   +1 more source