Results 81 to 90 of about 8,610,294 (201)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Investigations of smoothed particle hydrodynamics method for fluid-rigid body interactions
The aim of this project is to investigate the capability of smoothed particle hydrodynamics (SPH) method for fluid-rigid body interactions. SPH is one of the most widely used meshless methods which use particles to represent the system.
Sun, Fanfan
core +1 more source
Incompressible Lagrangian fluid flow with thermal coupling [PDF]
In this monograph is presented a method for the solution of an incompressible viscous fluid flow with heat transfer and solidification usin a fully Lagrangian description on the motion.
Oñate Ibáñez de Navarra, Eugenio +2 more
core +1 more source
This research incorporates the Bragg scattering mechanism in phononic crystal theory into fluid-structure interaction vibration suppression of hydraulic pipes.
Fuming Zhou +5 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Partitioned coupling of fluid-structure interaction for the simulation of floating wind turbines
Fluid-structure interaction problems appear in many different fields of application. An interesting and highly topical field is offshore renewable energy.
König, Marcel +4 more
core +1 more source
Wind turbine blade pitch fault is easy to cause unstable ultra-high load, which can lead to structural failure and damage. Firstly, the aerodynamic characteristics of NREL 5 MW wind turbine blades with pitch fault/success were analyzed based on the ...
GAO Wei +4 more
doaj
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source

