Results 151 to 160 of about 44,669 (268)

Ultrasensitive Detection of Porcine Epidemic Diarrhea Virus Infections Using Multivalent DNA Nanostructure‐Enabled Lateral Flow Assay

open access: yesAdvanced Healthcare Materials, EarlyView.
A multivalent DNA nanostructure‐enabled lateral flow assay was developed for rapid, ultrasensitive detection of porcine epidemic diarrhea virus (PEDV) nucleocapsid protein. Designer net‐shaped DNA nanostructures (DNA‐Net) presenting PEDV‐specific aptamers achieved ~1000‐fold enhanced binding, enabling detection of viral copies with Ct ≤ 37.42 within 10
Saurabh Umrao   +9 more
wiley   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină   +2 more
wiley   +1 more source

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo   +6 more
wiley   +1 more source

Engineered AuNPs/fMWCNT Nanocomposite Electrodes for High‐Sensitivity Methylglyoxal Sensing in Saliva and Sweat for Non‐Invasive Diabetes Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
An AuNPs/fMWCNT nanocomposite‐modified screen‐printed carbon electrode was engineered via sequential electrodeposition and integrated into a 3D‐printed microfluidic platform for ultrasensitive methylglyoxal detection. The non‐invasive sensing platform enables rapid analysis in saliva and sweat, highlighting strong potential for wearable point‐of‐care ...
Ahadul Amin Soshi   +3 more
wiley   +1 more source

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