Results 91 to 100 of about 392,640 (304)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Reduced formulation of a steady fluid-structure interaction problem with parametric coupling [PDF]

open access: yes, 2010
We propose a two-fold approach to model reduction of fluid-structure interaction. The state equations for the fluid are solved with reduced basis methods.
Lassila, Toni, Rozza, Gianluigi
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Unsteady Flow and Vibration Analysis of the Horizontal-Axis Wind Turbine Blade under the Fluid-Structure Interaction

open access: yesShock and Vibration, 2019
A 1.5 MW horizontal-axis wind turbine blade and fluid field model are established to study the difference in the unsteady flow field and structural vibration of the wind turbine blade under one- and two-way fluid-structure interactions.
Rui Zhu, Da-duo Chen, Shi-wei Wu
doaj   +1 more source

Structure and structure relaxation

open access: yes, 1998
A discrete--dynamics model, which is specified solely in terms of the system's equilibrium structure, is defined for the density correlators of a simple fluid.
A.P. Singh   +21 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

A Porosity Method to Describe Complex 3D-Structures Theory and Application to an Explosion

open access: yesActa Polytechnica, 2006
A theoretical method was developed to be able to describe the influence of structures of complex shape on a transient fluid flow without meshing the structures. Structures are considered as solid pores inside the fluid and act as an obstacle for the flow.
M.-F. Robbe
doaj  

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