Results 91 to 100 of about 1,057,935 (267)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Data Transfer Schemes in Rotorcraft Fluid-Structure Interaction Predictions

International Journal of Aerospace Engineering, 2018
For a CFD (computation fluid dynamics)/CSD (computational structural dynamics) coupling, appropriate data exchange strategy is required for the successful operation of the coupling computation, due to fundamental differences between CFD and CSD analyses.
Young H. You, Deokhwan Na, Sung N. Jung
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reduced formulation of a steady fluid-structure interaction problem with parametric coupling [PDF]

, 2010
We propose a two-fold approach to model reduction of fluid-structure interaction. The state equations for the fluid are solved with reduced basis methods.
Lassila, Toni, Rozza, Gianluigi
core   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Distributed Computational Method for Coupled Fluid Structure Thermal Interaction Applications

Journal of Algorithms & Computational Technology, 2010
The problem of effcient modeling and computation of the nonlinear interaction of fluid with a solid undergoing nonlinear deformation has remained a challenging problem in computational science and engineering.
E. Aulisa, S. Manservisi, P. Seshaiyer, A. Idesman   +3 more
doaj   +1 more source

Development of an integrated BEM approach for hot fluid structure interaction: BEST-FSI: Boundary Element Solution Technique for Fluid Structure Interaction [PDF]

As part of the continuing effort at NASA LeRC to improve both the durability and reliability of hot section Earth-to-orbit engine components, significant enhancements must be made in existing finite element and finite difference methods, and advanced ...
Banerjee, P. K., Dargush, G. F., Shi, Y.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Fluid–Structure Interaction and Flow Redistribution in Membrane-Bounded Channels

Energies, 2019
The hydrodynamics of electrodialysis and reverse electrodialysis is commonly studied by neglecting membrane deformation caused by transmembrane pressure (TMP).
Giuseppe Battaglia, Luigi Gurreri, Andrea Cipollina, Antonina Pirrotta, Svetlozar Velizarov, Michele Ciofalo, Giorgio Micale   +6 more
doaj   +1 more source