Results 111 to 120 of about 604,004 (299)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Fluid structure interaction

, 1999
Various formulations are reviewed in the case of linear vibration analysis of bounded fluid-structure systems for low modal density situations. Compressibility effects in the fluid for interior structural-acoustic problems, and free surface gravity effects, as well as for hydroelastic-sloshing interaction problems in the case of incompressible liquids,
openaire   +3 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Application of Finite Element Package in the Platform Development for Fluid-Structure Interaction Analysis [PDF]

, 2016
In the past, most of the fluid-structure interaction researches are concerned with structures of simple shapes or linear elastic materials because analysis programs for such structures are easy to be implemented or available as commercial packages ...
Tsai, Chang-Min;Teng, Chia-I;Wang, Chien-Kai
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Some Numerical Approaches to Solve Fluid Structure Interaction Problems in Blood Flow

Abstract and Applied Analysis, 2014
Some numerical approaches to solve fluid structure interaction problems in blood flow are reviewed. Fluid structure interaction is the interaction between a deformable structure with either an internal or external flow.
Aik Ying Tang, Norsarahaida Amin
doaj   +1 more source

Fluid structure interaction analysis of a calcified aortic valve [PDF]

, 2018
The aim of this paper is to investigate the effect of calcification of the aortic-valve leaflets on the flow pattern and hemodynamic parameters such as transvalvular pressure gradient and valve orifice area based on fluid structure interaction modelling ...
Cazzolato, B., Arjomandi, M., Sedaghatizadeh, N., Rezaei Kivi, A., Zander, A.   +4 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Development and Verification of Coupled Fluid–Structure Interaction Solver

Computation
Recent trends in aeroelastic analysis have shown a great interest in understanding the role of shock boundary layer interaction in predicting the dynamic instability of aircraft structural components at supersonic and hypersonic flows.
Avery Schemmel, Seshendra Palakurthy, Anup Zope, Eric Collins, Shanti Bhushan   +4 more
doaj   +1 more source