Results 151 to 160 of about 4,388,444 (360)

Hydrothorax and air fluid levels in the right chest – a diagnostic dilemma

, 2023
Malika M. Morar, T.B. Rangaka, AB Ogunrombi, Ahmed Abdalla   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Fluid responsiveness and changes in venous congestion and lung water during volume expansion in critically ill patients: a multicentre observational study. [PDF]

Crit Care
Si X, Cao D, Shi R, Song W, Antolini R, Beuzelin M, Blandina A, Botta F, Davì F, Rumi GL, Fracazzini M, Lauritano M, Rosa R, Gomes RF, Lim SY, Chen R, Wu J, Guan X, Pham T, Lai C, Monnet X.   +20 more
europepmc   +1 more source

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders.

New England Journal of Medicine, 1994
Lloyd Paul Aiello, Robert L. Avery, P. Arrigg, Bruce Keyt, H. Jampel, Sabera T. Shah, Louis R. Pasquale, Hagen Thieme, Mami Iwamoto, John Edward Park   +9 more
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Stochastische Euler-Euler-PDF-Methodik für das Zwei-Fluid-Modell und Anwendung auf kavitierende Strömungen der Automobilindustrie

, 2019
Martin R. Raquet
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Euler-scale dynamical correlations in integrable systems with fluid motion [PDF]

, 2020
Frederik Skovbo Møller, Gabriele Perfetto, Benjamin Doyon, Jörg Schmiedmayer   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Vaginal lavage fluid can serve as a reliable method for early screening of endometrial cancer: a proof-of-concept study. [PDF]

Front Oncol
Li Y, Ren P, Huang J, Tan S, Wang N.
europepmc   +1 more source