Results 71 to 80 of about 3,068,733 (292)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Non-Linear Creep of Spherical Container with Fluid Under Increasing Pressure
Engineering ProceedingsThis paper presents an analysis of the time-dependent response of a spherical container to internal pressure that increases over time. The wall of the container is relatively thin, in the sense that the wall thickness is negligible in comparison to the ...
Victor Rizov
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Global Journal of Public Health MedicineIntroduction: Recreational sports have gained popularity in South Africa. However, the dietary practices of participants remain unknown. The study evaluated the nutrient and timing of intake of recreational sports participants in the Vhembe District (VD),
Raymond Ramashidzha +2 more
doaj +1 more source
Psicologia: Reflexão e Crítica, 2012 Intelligence is commonly divided into two distinctive areas: fluid intelligence (Gf), which is understood as the skill of reasoning or intelligence as a process, and crystallized intelligence (Gc) that involves skills that are more related to learning ...
Ricardo Primi +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
مجلة النهرين للعلوم الهندسية, 2017 An experimental and numerical study was carried out to investigate heat transfer and flow characteristics through the tractor heat exchanger (radiator). The engine of the tractor is Diesel (compression ignition) engine type.
Kadhim F. Nasir
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Diuretic responses to Ringer's solution and 20% albumin at different arterial pressures
Physiological ReportsIntravenous volume loading is a common treatment when hypovolemia is a potential cause of oliguria. We studied whether the effectiveness of Ringer's solution and 20% albumin in inducing diuresis differs depending on the mean arterial pressure (MAP).
Robert G. Hahn +4 more
doaj +1 more source