Results 101 to 110 of about 68,602 (312)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Applying Mean-field Approximation to Continuous Time Markov Chains

open access: yes, 2013
The mean-field analysis technique is used to perform analysis of a systems with a large number of components to determine the emergent deterministic behaviour and how this behaviour modifies when its parameters are perturbed.
Senni, Valerio   +2 more
core  

Air-blown rivulet flow of a perfectly wetting fluid on an inclined substrate

open access: yes, 2008
Thin-film flows occur in a variety of physical contexts including, for example, industry, biology and nature, and have been the subject of considerable theoretical research.
Duffy, B.R.   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Dynamic equilibria of a nonisothermal fluid

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2018
In this paper, stationary dynamic equilibria of the rotating mass of a nonisothermal fluid are discussed within the accuracy limits of the Boussinesq approximation.
Evgeny Yu Prosviryakov
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The hydrodynamics of ship sections entering and exiting a fluid [PDF]

open access: yes, 1998
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.We study the hydrodynamics of wedge,knuckle and box cross-sectional profiles undergoing transient extreme motions, in particular forced entry and exit ...
Barringer, Ian Edward, Barringer, I.E.
core  

Quasilinear approximation for exact coherent states in parallel shear flows [PDF]

open access: yes, 2018
In the quasilinear approximation to the Navier–Stokes equation a minimal set of nonlinearities that is able to maintain turbulent dynamics is kept.
Qiang Yang   +7 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Instabilities in free-surface electroosmotic flows

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +1 more
core  

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