Results 101 to 110 of about 6,080,447 (331)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Scientific ReportsA new measuring method is presented that allows time-resolved quasi-simultaneous measurement of fibre orientation and flow velocity of a transparent fluid such as a substitute fluid for fresh concrete or polymer melt, thus enabling the flow-related fibre
Tim Vaupel +3 more
doaj +1 more source
Silverton Conference on Applications of the Zero Gravity Space Shuttle Environment to Problems in Fluid Dynamics [PDF]
The possible utilization of the zero gravity resource for studies in a variety of fluid dynamics and fluid-dynamic related problems was investigated. A group of experiments are discussed and described in detail; these include experiments in the areas of ...
Eisner, M.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number [PDF]
Wind Energy ScienceThis study shows an extensive analysis of dynamic stall on wind turbine airfoils, preparing for the development of a reduced-order model applicable to thick airfoils (t/c>0.21) in the future.
H. R. Kim +4 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Design automation based on fluid dynamics [PDF]
, 2017 This article was accepted and presented at the 9th International Workshop on Bio-Design Automation, Pittsburgh, Pennsylvania (2017).Microfluidic devices provide researchers with numerous advantages such as high throughput, increased sensitivity and ...
Densmore, Douglas +3 more
core
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Cerebrospinal-Fluid Dynamics [PDF]
New England Journal of Medicine, 1970 R A, Castellino, L M, Zatz, G L, DeNardo
openaire +2 more sources