Results 101 to 110 of about 383,488 (316)

Advanced optical measurement techniques for simultaneous fibre orientation and flow analysis complemented by machine learning

open access: yesScientific Reports
A new measuring method is presented that allows time-resolved quasi-simultaneous measurement of fibre orientation and flow velocity of a transparent fluid such as a substitute fluid for fresh concrete or polymer melt, thus enabling the flow-related fibre
Tim Vaupel   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Aerodynamic Analysis of Flow Characteristics Over Rotors Using Cfd Methods

open access: yes, 2016
Near future goals of the national aerospace industry for producing rotorcraft systems is boosting academic and industrial interest. In order to validate and accelerate design processes, computational methods are largely used.
Başaran, E.   +2 more
core  

Fluid Dynamics Experiments for Planetary Interiors

open access: yes, 2021
International audienceUnderstanding fluid flows in planetary cores and subsurface oceans, as well as their signatures in available observational data (gravity, magnetism, rotation, etc.), is a tremendous interdisciplinary challenge.
Noir, Jérôme André Roland; id_orcid   +9 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

The simulation of free surface flows with Computational Fluid Dynamics

open access: yes, 2008
Computational fluid dynamics is a powerful and versatile tool for the analysis of flow problems encountered in themaritime environment. The University of Southampton Fluid-Structure Interactions research group use ANSYS CFX tomodel a wide variety of flow
Tan, M.   +6 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Molecular Dynamics Simulation in Arbitrary Geometries for Nanoscale Fluid Mechanics

open access: yes, 2008
Simulations of nanoscale systems where fluid mechanics plays an important role are required to help design and understand nano-devices and biological systems.
Macpherson, Graham Bruce
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number [PDF]

open access: yesWind Energy Science
This study shows an extensive analysis of dynamic stall on wind turbine airfoils, preparing for the development of a reduced-order model applicable to thick airfoils (t/c>0.21) in the future.
H. R. Kim   +4 more
doaj   +1 more source

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