Results 141 to 150 of about 383,488 (316)

An experimental and computational analysis of buoyancy driven flows by laser sheet tomography, particle image velocimetry and computational fluid dynamics

open access: yes, 1997
This paper contains details of a three pronged investigation into the development of a buoyant jet impinging on a wall in a closed vessel. The development of the flow was measured experimentally by particle image velocimetry (PIV) and laser sheet ...
Scanlon, TJ   +11 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Numerical Investigation of Winglets Used To Improve the Flying Performance of Unmanned Aerial Vehicle

open access: yes, 2016
In this study, the aerodynamic forces, velocity and pressure distributions are analyzed on SD7062 wing profile with CFD program FLUENT. Calculations are made for one clean wing and 3 different winglets named End-Plate, Blended and Scimitar which are ...
Çoban, A. B., Kaynak, Ünver
core  

The Land Component LM4.1 of the GFDL Earth System Model ESM4.1: Model Description and Characteristics of Land Surface Climate and Carbon Cycling in the Historical Simulation

open access: yesJournal of Advances in Modeling Earth Systems
We describe the baseline model configuration and simulation characteristics of the Geophysical Fluid Dynamics Laboratory (GFDL)'s Land Model version 4.1 (LM4.1), which builds on component and coupled model developments over 2013–2019 for the coupled ...
E. Shevliakova   +19 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Drag Analysis of a Supersonic Fighter Aircraft

open access: yes, 2016
For aircraft design, drag optimization is very important for having better flight performance and less fuel consumption. In this study, drag effects of fuselage, wing and tail section are separately analyzed using a generic F-16 fighter aircraft model in
Kurtulus D. F.   +3 more
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Toward Understanding Polar Heat Transport Enhancement in Subglacial Oceans on Icy Moons

open access: yesGeophysical Research Letters
The interior oceans of several icy moons are considered as affected by rotation. Observations suggest a larger heat transport around the poles than at the equator.
Robert Hartmann   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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