Results 31 to 40 of about 608,013 (260)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
TASK Quarterly, 2001 The lifetime estimation of power station structures and components, subjected to fatigue loading, is essential for determining the moment of repair or replacement. Therefore the degradation behaviour and damage development within material should be very
MARCIN BIELECKI +3 more
doaj
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Development of a computational framework for low-Reynolds number propeller aeroacoustics
Archives of MechanicsThe paper focuses on the development and validation of a new computational framework designed for the prediction of tonal and broadband noise radiation of propellers of unmanned aerial vehicles (UAVs) operating in the low-Reynolds number regime.
O. Szulc, T. Suresh, P. Flaszyński
doaj +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
PROPOSAL OF MODERNISATION OF A STEAM TURBINE STAGE BEFORE EXTRACTION, CFD AND CSD ANALYSIS
TASK Quarterly, 2002 The paper presents an idea and analysis of application of a new solution of a stage before extraction in the modernised LP part of 200MW turbines with ND37 exhaust.
ANDRZEJ GARDZILEWICZ +6 more
doaj
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
NOVEL ELECTROSTATIC WIND ENERGY CONVERTER: AN OVERVIEW
TASK Quarterly, 2015 The article discusses the historical development and embodiments of the concept of generating electricity from wind energy without the use of wind turbines, so called electrostatic bladeless generators or generators without moving parts.
HELENA NOWAKOWSKA +3 more
doaj +1 more source