Results 91 to 100 of about 1,118,588 (301)

Modeling Fluid Forces in the Dive Start of Competitive Swimming

Journal of Biomechanical Science and Engineering, 2010
The objective of this study was to construct a fluid force model for the dive start. The fluid force model is incorporated into a swimming human simulation model SWUM, which has been developed by the authors.
Hirokazu KIUCHI, Motomu NAKASHIMA, Kuangyou B. CHENG, Mont HUBBARD   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Transformations in Flow Characteristics and Fluid Force Reduction with Respect to the Vegetation Type and Its Installation Position Downstream of an Embankment

Fluids
Compound mitigation systems, integrations of natural and engineering structures against the high inundating current from tsunamis or storm surges, have garnered significant interest among researchers, especially following the Tohoku earthquake and ...
A H M Rashedunnabi, Norio Tanaka, Md Abedur Rahman   +2 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Effects of Four Types of Pre-swirls on the Leakage, Flow Field, and Fluid-Induced Force of the Rotary Straight-through Labyrinth Gas Seal

Chinese Journal of Mechanical Engineering, 2019
The labyrinth seal in turbomachinery is a key element that restricts leakage flow among rotor-stator clearances from high-pressure regions to low-pressure regions.
Qingfeng Wang, Lidong He
doaj   +1 more source

Self-charging metering and dispensing device for fluids [PDF]

, 1984
A self-metering and dispensing device for fluids obtained from a pressurized fluid supply is discussed. Tubing and valving means permit the introduction of fluid into and discharge from a closed cylindrical reservoir.
Hooper, S. L., Setzer, D.
core   +1 more source

Force dipoles and stable local defects on fluid vesicles

, 2013
An exact description is provided of an almost spherical fluid vesicle with a fixed area and a fixed enclosed volume locally deformed by external normal forces bringing two nearby points on the surface together symmetrically.
A. Gray, A. M. Polyakov, A. T. Fomenko, Jemal Guven, Pablo Vázquez-Montejo, T. J. Willmore, W. Helfrich   +6 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Spiral Waves in Driven Dusty Plasma Medium: Generalized Hydrodynamic Fluid Description

, 2017
Spiral waves are observed in many natural phenomena. They have been extensively represented by the mathematical FitzHugh-Nagumo (FHN) model [Barkley et al., Phys. Rev. A 42, 2489 (1990)] of excitable media.
Das, Amita, Kumar, Sandeep, Patel, Bhavesh   +2 more
core   +1 more source