Results 81 to 90 of about 1,191,394 (284)

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Construction of Carbon Dioxide Responsive Graphene Point Imbibition and Drainage Fluid and Simulation of Imbibition Experiments

Processes
The global oil and gas exploration targets are gradually moving towards a new field of oil and gas accumulation with nanopore throats, ranging from millimeter scale to micro-nano pore throats. The development method of tight oil reservoirs is different from that of conventional oil reservoirs, and the development efficiency is constrained.
Peng Yin, Fang Shi, Mingjian Luo, Jingchun Wu, Yanan Yu, Chunlong Zhang, Bo Zhao   +6 more
openaire   +1 more source

Capillary tension and imbibition sequester frack fluid in Marcellus gas shale [PDF]

Proceedings of the National Academy of Sciences, 2012
In a recent issue of PNAS, Warner et al. (1) interpreted local ground water chemistry in the Appalachian Basin as a signal for cross-formational pathways where natural migration of brine from the deep formations may be ongoing today. The implication of this paper is that the Marcellus is leaking now naturally, without any human assistance, and that if ...
openaire   +2 more sources

Oxygen Vacancy‐Mediated Bi─O Unsaturation Coordination in BiOCl for Efficient Photocatalytic Water Purification

Advanced Science, EarlyView.
The incorporation of oxygen vacancies (OVs) presents a viable strategy for fine‐tuning the photocatalytic prowess of BiOCl. A reliable hydrogen annealing reduction technique is employed to precisely design OVs, thereby optimizing the light absorption capacity, as well as the efficiency of carrier migration and separation in BiOCl.
Shuaihao Ma, Jianglong Kong, Shidong Zhang, Wentao Li, Ling Yan, Deng Long, Xinglin Yu, Dawei Wang, Zheng Han, Sihan Ma, Lin Wang, Guang Ran   +11 more
wiley   +1 more source

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

A Multiscale Study on Shale Wettability: Spontaneous Imbibition Versus Contact Angle

Water Resources Research, 2019
Environmental and technical issues associated with hydraulic fracturing fluid leak‐off and its low recovery in clay‐rich shale reservoirs has challenged the energy sector.
Mohammed Abdul Qadeer Siddiqui, Xiao Chen, Stefan Iglauer, Hamid Roshan   +3 more
doaj   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Pore-scale investigation of forced imbibition in porous rocks through interface curvature and pore topology analysis

Journal of Rock Mechanics and Geotechnical Engineering
Forced imbibition, the invasion of a wetting fluid into porous rocks, plays an important role in the effective exploitation of hydrocarbon resources and the geological sequestration of carbon dioxide. However, the interface dynamics influenced by complex
Jianchao Cai, Xiangjie Qin, Han Wang, Yuxuan Xia, Shuangmei Zou   +4 more
doaj   +1 more source