Results 151 to 160 of about 37,365 (307)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Melting of sediments in the deep mantle produces saline fluid inclusions in diamonds. [PDF]

Sci Adv, 2019
Förster MW, Foley SF, Marschall HR, Alard O, Buhre S.   +4 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Fluid inclusions in chromite from a pyroxenite dike of the Pindos ophiolite complex

, 2005
Chromitite occurrences in the Pindos ophiolite complex are located in elongated dunite bodies hosted in harzburgite of the mantle sequence, and show a compositional variation from high-Al to high-Cr type.
Al-Boghdady, A., Economou-Eliopoulos, M.
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Silicate melt and fluid inclusions in the grey tuffs of Monte dei Porri, Island of Salina, Aeolian Islands, Italy

, 2011
Description of fluid and melt inclusions in pyroclastics of Monte dei Porri volcano eruption at Salina, Aeolian Islands ...
DE VIVO, BENEDETTO, MESSINA A., DOHERTY A., BODNAR R. J.   +3 more
core  

Fluid inclusions: tiny windows into global paleo-environments. [PDF]

Commun Earth Environ
Bekaert DV, Avice G, Marty B.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Breathing life into the boring billion: Direct constraints from 1.4 Ga fluid inclusions reveal a fair climate and oxygenated atmosphere. [PDF]

Proc Natl Acad Sci U S A
Park JG, Hudgins MN, Fralick P, Shelley JT, Schaller MF.   +4 more
europepmc   +1 more source

Paleoclimatic information recorded in fluid inclusions in halites from Lop Nur, Western China. [PDF]

Sci Rep, 2017
Sun XH, Zhao YJ, Liu CL, Jiao PC, Zhang H, Wu CH.   +5 more
europepmc   +1 more source