Results 61 to 70 of about 31,594 (263)

Characterization of fluid inclusions and sulfur isotopes in the Iju porphyry copper deposit, North West of Shahr-e-Babak

open access: yesJournal of Economic Geology, 2017
Introduction The Iju porphyry copper deposit is located in the southern part of the Urumieh-Dokhtar magmatic arc (Dehaj-Sarduieh belt) within the Kerman copper belt (Dimitrijevic, 1973).
Malihe Golestani   +3 more
doaj   +1 more source

Gas migration for terrestrial gas hydrates in the Juhugeng mining area of Muli basin, Qilian Mountains, Northwest China

open access: yesEnergy Exploration & Exploitation, 2020
The Juhugeng mining area in the Qilian Mountains is the only district of China where terrestrial gas hydrate has been found. This paper aimed at studying the gas migration for gas hydrates based on fluid inclusion and apatite fission track experiments ...
Anmin Wang   +5 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Fluid inclusions in reservoirs of Weixinan Sag, Beibuwan Basin

open access: yesPetroleum Exploration and Development, 2008
: To make sure the petroleum migrating direction and pool-forming model in the Weixinan sag, 4 wells were chosen to do research on fluid inclusions and petrography. The petroleum inclusions have three types: type I occurs in early cracks of quartz debris
Ping LIU   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

2D Hydro‐Mechanical‐Chemical Modeling of (De)hydration Reactions in Deforming Heterogeneous Rock: The Periclase‐Brucite Model Reaction

open access: yesGeochemistry, Geophysics, Geosystems, 2020
Deformation at tectonic plate boundaries involves coupling between rock deformation, fluid flow, and metamorphic reactions, but quantifying this coupling is still elusive.
Stefan M. Schmalholz   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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