Results 91 to 100 of about 504,909 (326)

Parabolic equations on uniformly regular Riemannian manifolds and degenerate initial boundary value problems [PDF]

open access: yes, 2014
In this work there is established an optimal existence and regularity theory for second order linear parabolic differential equations on a large class of noncompact Riemannian manifolds.
Amann, Herbert
core  

Morphing quantum mechanics and fluid dynamics

open access: yes, 2003
We investigate the effects of given pressure gradients on hydrodynamic flow equations. We obtain results in terms of implicit solutions and also in the framework of an extra-dimensional formalism involving the diffusion/Schrodinger equation.Comment ...
Curtright, Thomas, Fairlie, David
core   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Extra mass flux in fluid mechanics

open access: yes, 2016
The conditions of existence of extra mass flux in single component dissipative non-relativistic fluids are clarified. By considering Galilean invariance we show that if total mass flux is equal to total momentum density, then mass, momentum, angular ...
Grmela, Miroslav   +2 more
core   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

On Integrability and Exact Solvability in Deterministic and Stochastic Laplacian Growth

open access: yes, 2019
We review applications of theory of classical and quantum integrable systems to the free-boundary problems of fluid mechanics as well as to corresponding problems of statistical mechanics.
Loutsenko, Igor, Yermolayeva, Oksana
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

The influence of flow parameters on the transition to turbulence in pulsatile flow

open access: yesEPJ Web of Conferences, 2014
The paper is focused on the experimental investigation of the flow parameters influence (stationary component of flow, frequency, amplitude) on the transition to turbulence in pulsatile flow in a straight square channel.
Schmirler M.   +4 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

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