Results 81 to 90 of about 2,155,044 (206)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Unified lagrangian formulation for fluid and solid mechanics, fluid-structure interaction and coupled thermal problems using the PFEM [PDF]
, 2015 The objective of this work is the derivation and implementation of a unifed Finite Element formulation for the solution of uid and solid mechanics, Fluid-Structure Interaction (FSI) and coupled thermal problems.Postprint (published ...
Oñate Ibáñez de Navarra, Eugenio +2 more
core
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Dispersion Mechanisms of a Tidal River Junction in the Sacramento–San Joaquin Delta, California
San Francisco Estuary and Watershed Science, 2014 doi: http://dx.doi.org/10.15447/sfews.2014v12iss4art1In branching channel networks, such as in the Sacramento–San Joaquin River Delta, junction flow dynamics contribute to dispersion of ecologically important entities such as fish, pollutants, nutrients,
Karla T. Gleichauf +4 more
doaj
Multiphase flow modelling for sustainable deep-sea mining [PDF]
EPJ Web of ConferencesDeep-sea mining extracts polymetallic sulphides at extreme depths, requiring sustainable approaches to minimize environmental impact. Seabed milling, particle transport, and a hydrocyclone based containment system are modelled in CFD-DEM simulations to ...
Saha Suharto +5 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Aeroelastic Subcritical Bifurcations Caused by Two Typical Structural Nonlinearities
气体物理Current research on aeroelastic bifurcation predominantly focuses on two-dimensional problems, and there is a lack of effective methods for studying bifurcation in three-dimensional aeroelastic systems, making it difficult to apply such research in ...
Chengde HUANG +3 more
doaj +1 more source
AIP Advances, 2018 Cavitating flow near free surface is a complicated issue and may provide new inspiration on high-speed surface cruising. This study observes stable supercavitating flow as a new phenomenon in a launch experiment of axisymmetric projectile when the upper ...
Chang Xu +5 more
doaj +1 more source