Results 91 to 100 of about 528,982 (293)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Dispersion Mechanisms of a Tidal River Junction in the Sacramento–San Joaquin Delta, California
San Francisco Estuary and Watershed Science, 2014 doi: http://dx.doi.org/10.15447/sfews.2014v12iss4art1In branching channel networks, such as in the Sacramento–San Joaquin River Delta, junction flow dynamics contribute to dispersion of ecologically important entities such as fish, pollutants, nutrients,
Karla T. Gleichauf +4 more
doaj
The influence of flow parameters on the transition to turbulence in pulsatile flow
EPJ Web of Conferences, 2014 The paper is focused on the experimental investigation of the flow parameters influence (stationary component of flow, frequency, amplitude) on the transition to turbulence in pulsatile flow in a straight square channel.
Schmirler M. +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Method for the evaluation of minor losses in pulsatile laminar fluid flow
EPJ Web of Conferences, 2014 This article focuses on description and evaluation of the size of the minor losses in pulsatile laminar flow. It describes a method for determination of minor losses with respect to the phase delay between pressure waveforms and flow waveforms. The whole
Netřebská H. +4 more
doaj +1 more source
Study of filtration mechanics and sampling techniques, phase 4 Annual report, 1967-1968 [PDF]
Filtration mechanics and fluid ...
Fitch, E. C., Long, D. E., Reed, R. E.
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Multiphase flow modelling for sustainable deep-sea mining [PDF]
EPJ Web of ConferencesDeep-sea mining extracts polymetallic sulphides at extreme depths, requiring sustainable approaches to minimize environmental impact. Seabed milling, particle transport, and a hydrocyclone based containment system are modelled in CFD-DEM simulations to ...
Saha Suharto +5 more
doaj +1 more source
Violation of Bell's inequality in fluid mechanics [PDF]
, 2013 We show that a classical fluid mechanical system can violate Bell's inequality because the fluid motion is correlated over large ...
Anderson, Ross, Brady, Robert
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source