Results 101 to 110 of about 418,311 (280)
Flow compensating pressure regulator [PDF]
, 1978 An apparatus for regulating pressure of treatment fluid during ophthalmic procedures is described. Flow sensing and pressure regulating diaphragms are used to modulate a flow control valve.
Baehr, E. F.
core +1 more source
Self-gravitating fluid flows with Gowdy symmetry near cosmological singularities
, 2017 We consider self-gravitating fluids in cosmological spacetimes with Gowdy symmetry on the torus $T^3$ and, in this class, we solve the singular initial value problem for the Einstein-Euler system of general relativity, when an initial data set is ...
Beyer, Florian, LeFloch, Philippe G.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Syndrome of inappropriate antidiuretic hormone secretion: Revisiting a classical endocrine disorder
Indian Journal of Endocrinology and Metabolism, 2011 Hyponatremia occurs in about 30% of hospitalized patients and syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia.
Binu P Pillai +2 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
BMC Nephrology, 2017 Background Adherence to diet recommendations, fluid restriction, prescribed medications, and attendance at hemodialysis (HD) sessions are essential for optimal and effective treatment of patients with end-stage renal disease. No data regarding this issue
Karam Sh. Naalweh +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Tolvaptan use during hyperhydration in paediatric intracranial lymphoma with SIADH
Endocrinology, Diabetes & Metabolism Case Reports, 2016 An 11-year-old boy developed severe syndrome of inappropriate antidiuretic hormone secretion (SIADH) after diagnosis of an intracranial B-cell lymphoma. His sodium levels dropped to 118–120 mmol/L despite 70% fluid restriction.
Ruben H Willemsen +6 more
doaj +1 more source
Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery
New England Journal of Medicine, 2018 Guidelines to promote the early recovery of patients undergoing major surgery recommend a restrictive intravenous-fluid strategy for abdominal surgery. However, the supporting evidence is limited, and there is concern about impaired organ perfusion.In a pragmatic, international trial, we randomly assigned 3000 patients who had an increased risk of ...
Myles, PS +17 more
openaire +4 more sources