Understanding Patients' Experiences and Adherence Challenges with Dietary and Fluid Restriction in End-Stage Kidney Disease: A Qualitative Study. [PDF]
Liao Y +5 more
europepmc +1 more source
Tolvaptan versus fluid restriction in acutely hospitalised patients with moderate-profound hyponatraemia (TVFR-HypoNa): design and implementation of an open-label randomised trial. [PDF]
Warren AM +4 more
europepmc +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Furosemide plus oral sodium chloride for syndrome of inappropriate antidiuresis after fluid restriction failure. [PDF]
Chienwichai K +6 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Fluid restriction vs liberal intake in patients with heart failure: a meta-analysis of randomized trials. [PDF]
Bielecka-Dabrowa A +3 more
europepmc +1 more source
Fluid restriction in dialysis patients [PDF]
openaire +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Fluid management during neurosurgical procedures
Historical bias has favored fluid restriction in patients with brain pathology. The efficacy of fluid restriction on brain edema remains unproven, and the consequences of fluid restriction, if pursued to the point of hypovolemia, can be devastating ...
C. Tommasino, V. Picozzi
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