Results 71 to 80 of about 1,767,668 (275)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Faktor – Faktor yang Mempengaruhi Kecemasan Orang Tua pada Anak Pra-operasi Di Ruang Bedah Anak

NERS Jurnal Keperawatan, 2019
Noncompliance with fluid restriction is a problem in patients undergoing hemodialysis. The impact suchs pulmonary edema increases the risk of cardiovascular disorders, and hypertension. This study aims to determine the relationship of family support and
Dwi Novrianda, Hermalinda, Musymiratul Fauziah   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Effect of intraoperative fluid optimisation on renal function in patients undergoing emergency abdominal surgery; a randomised controlled pilot study (ISRCTN 11799696) Fluid optimisation for emergency surgery [PDF]

, 2008
<b>Background:</b> Emergency abdominal surgery carries a high risk of postoperative morbidity and mortality. Goal directed therapy has been advocated to improve outcome in high-risk surgery.
McCreath, B., Kinsella, J., Hay, A., Harten, J., McMillan, D.C., McArdle, C.S., Crozier, J.E.M.   +6 more
core   +1 more source

The Effect of Education Given to Hemodialysis Patients on Blood Pressure and Weight Gain

Turkish Journal of Nephrology, 2019
OBJECTIVE: This study aimed to investigate effect of salt and fluid restriction education for patients undergoing hemodialysis and nonadherent to fluid restriction treatment on blood pressure and weight gain.
Yasemin TURGUT KURT, Emre ERDEM, Coşkun KAYA, Ahmet KARATAŞ, Nurol ARIK   +4 more
doaj  

Dukungan Keluarga dan Lama Dialisis Sebagai Faktor Berhubungan Dengan Kepatuhan Pembatasan Cairan Pasien Gagal Ginjal Kronik

NERS Jurnal Keperawatan, 2019
Noncompliance with fluid restriction is a problem in patients undergoing hemodialysis. The impact suchs pulmonary edema increases the risk of cardiovascular disorders, and hypertension. This study aims to determine the relationship of family support and
Tiurmaida Simandalahi, Siska Sakti, Ropendi Pardede   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Structural and functional analysis of the symmetrical type I restriction endonuclease R.EcoR124INT [PDF]

, 2012
Type I restriction-modification (RM) systems are comprised of two multi-subunit enzymes, the methyltransferase (∼160 kDa), responsible for methylation of DNA, and the restriction endonuclease (∼400 kDa), responsible for DNA cleavage. Both enzymes share a
Philip Callow, Anna Swiderska, Taylor, JE, Jean-Baptiste Artero (176290), Callow, P, James E Taylor, Kneale, G, Jean-Baptiste Artero, Geoff Kneale, Geoff Kneale (22086), Anna Swiderska (176286), Philip Callow (176295), Swiderska, A, Artero, JB, James E. Taylor (176282), Taylor, J., Swiderska Anna, Callow Philip, Artero Jean-Baptiste, Kneale Geoff, Artero, J., Kneale, Geoff, Callow, P., Taylor James E., Swiderska, Anna   +24 more
core   +1 more source

Effectiveness of thirst intervention package on thirst intensity and thirst distress among patients of heart failure with fluid restriction at a tertiary care center

Heart India
Background: Heart failure (HF) is a global burden since it is a widespread, expensive, and potentially life-threatening illness. Thirst is one of the most common symptoms of HF as well a major concern for patients.
Farah Naaz, Suchana Roy Bhowmik, Akshyaya Pradhan   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source