Results 111 to 120 of about 1,061,828 (287)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Distributed Computational Method for Coupled Fluid Structure Thermal Interaction Applications

open access: yesJournal of Algorithms & Computational Technology, 2010
The problem of effcient modeling and computation of the nonlinear interaction of fluid with a solid undergoing nonlinear deformation has remained a challenging problem in computational science and engineering.
E. Aulisa   +3 more
doaj   +1 more source

Fluid structure interaction

open access: yes, 1999
Various formulations are reviewed in the case of linear vibration analysis of bounded fluid-structure systems for low modal density situations. Compressibility effects in the fluid for interior structural-acoustic problems, and free surface gravity effects, as well as for hydroelastic-sloshing interaction problems in the case of incompressible liquids,
openaire   +3 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Strong solutions in $L^2$ framework for fluid-rigid body interaction problem - mixed case

open access: yes, 2018
The paper deals with the well-posedness of the strong solution of fluid-structure interaction problem when the mixed boundary conditions are ...
Baba, Hind Al   +3 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Influence of Fluid-Structure Interaction on Microcantilever Vibrations: Applications to Rheological Fluid Measurement and Chemical Detection [PDF]

open access: yes, 2013
At the microscale, cantilever vibrations depend not only on the microstructure’s properties and geometry but also on the properties of the surrounding medium.
Brand, Oliver   +7 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Some Numerical Approaches to Solve Fluid Structure Interaction Problems in Blood Flow

open access: yesAbstract and Applied Analysis, 2014
Some numerical approaches to solve fluid structure interaction problems in blood flow are reviewed. Fluid structure interaction is the interaction between a deformable structure with either an internal or external flow.
Aik Ying Tang, Norsarahaida Amin
doaj   +1 more source

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