Results 81 to 90 of about 1,066,100 (336)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Fluid-structure interaction modeling with chimera grids in NSMB*
ESAIM: Proceedings and Surveys, 2014 The paper presents the last few years of research at ICUBE, Team MECAFLU in the “Instabilité, Turbulence, Diphasique”group on the simulations of fluid-structure interactions applied to falling bodies using the NSMB solver.
Hoarau Yannick +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Fluid-particle-structure interaction in single shot peening
Scientific ReportsShot peening is a widely used cold-working process. Physical phenomena of shot peening are analyzed using the developed fluid-particle-structure coupled solver. The influences of the flow field and shot peening parameters such as the shot impact velocity
Yusuke Mizuno +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A fluid-structure interaction method for soft particle transport in curved microchannels
, 2023 Dario De Marinis +3 more
openalex +1 more source
Semigroup Well-posedness of A Linearized, Compressible Fluid with An Elastic Boundary
, 2017 We address semigroup well-posedness of the fluid-structure interaction of a linearized compressible, viscous fluid and an elastic plate (in the absence of rotational inertia).
Avalos, George +2 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source