Results 51 to 60 of about 594,017 (304)

Pediatric Fluid Therapy

Veterinary Clinics of North America: Small Animal Practice, 2008
Many conditions of pediatric patients require fluid therapy. Depending on the veterinarian's assessment of hydration and perfusion status, fluids can be administered orally, subcutaneously, intraperitoneally, intravenously, or by the intraosseous route.
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The role of brain natriuretic peptide in predicting renal outcome and fluid management in critically ill patients

Journal of the Formosan Medical Association, 2015
Fluid overload is associated with acute kidney injury (AKI) and mortality. There is no convenient precise method to guide fluid therapy in critically ill patients.
Yu-Hsiang Chou, Yen-Fu Chen, Szu-Yu Pan, Tao-Min Huang, Feng-Jung Yang, Wen-Ching Shen, Yung-Ming Chen   +6 more
doaj   +1 more source

Intravenous maintenance fluid therapy practice in the pediatric acute and critical care settings: a European and Middle Eastern survey [PDF]

, 2022
Claire Morice, Fahad Alsohime, Huw Mayberry, Lyvonne N. Tume, David Brossier, Frédéric V. Valla, Capucine Didier, Clémence Moullet, Corinne Jotterand Chaparro, Eva Kühlwein, Fabrizio Chiuslo, Florence Porcheret, Fortesa Mehmeti, Hakan Tekgüç, Ilia Stavroula, Isabelle Goyer, Jesús López‐Herce, John Pappachan, Jorge López, Konstantinos Tziouvas, Leonardo Costa, Leonor Boto, Luise V. Marino, Luregn Schapbach, Magdalena Mierzewska-Schmidt, María Miñambres Rodríguez, Martin C. J. Kneyber, Monica Fae, Nyandat L. Joram, Peter Kenderessy, Sascha Verbruggen, Shancy Rooze, Sophie Beldjilali, Sophie Beldjilali   +33 more
openalex   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children— a systematic review and meta-analysis [PDF]

, 2022
David Brossier, Lyvonne N. Tume, Anaïs R. Briant, Corinne Jotterand Chaparro, Clémence Moullet, Shancy Rooze, Sascha Verbruggen, Luise V. Marino, Fahad Alsohime, Sophie Beldjilali, Fabrizio Chiusolo, Leonardo Costa, Capucine Didier, Stavroula Ilia, Nyandat L. Joram, Martin C. J. Kneyber, Eva Kühlwein, Jorge López, Jesús López‐Herce, Huw Mayberry, Fortesa Mehmeti, Magdalena Mierzewska-Schmidt, María Miñambres Rodríguez, Claire Morice, John Pappachan, Florence Porcheret, Leonor Boto, Luregn J. Schlapbach, Hakan Tekgüç, Konstantinos Tziouvas, Jean‐Jacques Parienti, Isabelle Goyer, Frédéric V. Valla, the Metabolism Endocrinology and Nutrition section of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC)   +33 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Current Trends in Volume Replacement Therapy and the Use of Synthetic Colloids in Small Animals—An Internet-Based Survey (2016)

Frontiers in Veterinary Science, 2017
The use of synthetic colloids (SCs), particularly hydroxyethyl starch (HES), in people has changed in recent years following new evidence raising concerns about their efficacy and safety.
Ivayla D. Yozova, Judith Howard, Nadja E. Sigrist, Katja-Nicole Adamik   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source