Results 51 to 60 of about 426 (262)

A FEM-DEM model for immersed granular flows: From unresolved to semi-resolved scales [PDF]

EPJ Web of Conferences
This work presents a coupling between the Finite Element Method (FEM) and the Discrete Element Method (DEM) to simulate immersed granular flows, transitioning from an unresolved to a semi-resolved representation.
Henry Michel, Cote Martinez Laura Valentina, Jommi Cristina, Hicks Michael, Lambrechts Jonathan, Legat Vincent, Cabrera Miguel   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Sistemas de lógica difusa en el proceso de secado de café en lecho fluidizado

Ingeniería e Investigación, 2005
En el presente trabalo de investigación se experimenta con un sistema de secado de granos en lecho fluidizado. Se utiliza un prototipo en el cual se seca café utilizando varias temperaturas del aire de secado (López, 2002).
Elkin Mauricio López Fontal
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

The fluid dynamics of a downer fluidised bed using a cluster-based approach (CBA)

Ingeniería e Investigación, 2010
The fluid dynamics of a downer reactor were numerically resolved by adapting a mathematical conservation model. The mathematical model was based on the solid and fluid properties and physical characteristics using a cluster-based approach (CBA ...
Germán González Silva, Antônio Carlos Luz Lisboa, Héctor José Ciro Velasquéz   +2 more
doaj  

Flowability of granular materials with industrial applications - An experimental approach

EPJ Web of Conferences, 2017
Designing bulk material handling equipment requires a thorough understanding of the mechanical behaviour of powders and grains. Experimental characterization of granular materials is introduced focusing on flowability.
Torres-Serra Joel, Romero Enrique, Rodríguez-Ferran Antonio, Caba Joan, Arderiu Xavier, Padullés Josep-Manel, González Juanjo   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Experimental study and characterisation of a novel two stage bubbling fluidised bed gasification process utilising municipal waste wood

Fuel Processing Technology
Biomass gasification has increased due to its ability to provide high-temperature heat, making it promising for the decarbonisation of industrial processes.
M. Kresta, D. Gurtner, L. Nohel, A. Hofmann, C. Pfeifer   +4 more
doaj   +1 more source