Results 61 to 70 of about 11,951 (302)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
An Analytical Study for Fluidized Bed Cooler Thermal Design [PDF]
Engineering and Technology Journal, 2015 The paper describes an investigation for the thermal design of a fluidized bed cooler and prediction of heat transfer rate among the media categories. It is devoted to the thermal design of such equipment and their application in the industrial fields ...
Damiaa Saad Khudor
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modeling the size of hydrophilic nanoparticles during fluidization with emphasis on the role of vapor of polar materials [PDF]
مجله مدل سازی در مهندسی, 2018 In this study, a comprehensive force balance model is developed to estimate the equilibrium size of agglomerates formed during the fluidization of nanoparticles with considering the importance of hydrogen bond, van der Waals and gravitational forces ...
Maryam Tahmasebpoor +1 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Segregation and Fluidization Behavior of Poly-disperse Mixtures of Biomass and Inert Particles
Chemical Engineering Transactions, 2017 This paper reports on the results of an experimental study aimed at investigating the fluidization and segregation behavior of poly-disperse binary mixtures consisting of small and dense inert particles mixed with less dense and coarse pieces of biomass ...
P. Brachi +4 more
doaj +1 more source
On the minimum fluidization velocity in 2D fluidized beds [PDF]
Powder Technology, 2011 In the present study, a new correlation for the determination of the minimum fluidization velocity in 2D fluidized beds was developed. The proposed correlation was based on the experimental results obtained in 2D fluidized beds with different particle sizes, bed thicknesses and bed heights.
Sánchez-Delgado, Sergio +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Dynamical weakening of pyroclastic flows by mechanical vibrations
EPJ Web of Conferences, 2017 Dynamical weakening of dense granular flows plays a critical role on diverse geological events such as seismic faulting and landslides. A common feature of these processes is the development of fluid-solid relative flows that could lead to fluidization ...
Valverde Jose Manuel +2 more
doaj +1 more source
Fluidization Dynamics of Hydrophobic Nanosilica with Velocity Step Changes
Applied Sciences, 2020 Nanosilica is widely used in various applications, with its market expected to grow over USD 5 billion by 2025. The fluidized bed technology, owing to its intimate contact and efficient mixing of phases, is ideally suited for the large scale processing ...
Ebrahim H. Al-Ghurabi +3 more
doaj +1 more source