Results 61 to 70 of about 1,405,837 (289)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Prediction and Visualization of Channel Characteristics for Lost Circulation of Drilling Fluid in Fractured Formations

Geofluids
Accurate characterization of the feature parameters of lost circulation channels in fractured formations is of great significance for assessing lost circulation risk and designing effective leakage prevention and plugging strategies.
Jinjun Hu, Sijia Ma, Tie Geng, Wei Zhang, Anguo Xu, Xiaodong Liu, Shuai Zhang   +6 more
doaj   +1 more source

A novel soot concentration field estimator applied to sooting ethylene/air laminar flames

Engineering Applications of Computational Fluid Mechanics, 2019
Soot formation modeling, when incorporated into computational fluid dynamics of industrial devices, can be numerically prohibitive. Nonetheless, there remains a significant push to predict soot formation, so as to aid in environmentally sustainable ...
L. Zimmer, S. Kostic, S. B. Dworkin
doaj   +1 more source

Thermal Management of Li-Ion Batteries With Single-Phase Liquid Immersion Cooling

IEEE Open Journal of Vehicular Technology, 2020
Development of effective thermal management techniques is essential in enabling further technical advances and wide public acceptance of lithium-ion based battery electrical storage.
David W. Sundin, Sebastian Sponholtz
doaj   +1 more source

Purely radiative perfect fluids

, 2007
We study `purely radiative' (div E = div H = 0) and geodesic perfect fluids with non-constant pressure and show that the Bianchi class A perfect fluids can be uniquely characterized --modulo the class of purely electric and (pseudo-)spherically symmetric
B Bastiaensen, Bonnor W B, Bonnor W B, Collins C B, Collins C B, Ellis G F R, H R Karimian, Hogan P, Kramer D, L Wylleman, Lozanovski C, Lozanovski C, Lozanovski C, MacCallum M A H, N Van den Bergh, Raychaudhuri A K, Trumper M, Van den Bergh N, Van den Bergh N, Van den Bergh N Bastiaensen B Karimian R H Wylleman L, van Elst H, Wylleman L   +21 more
core   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Machine learning approach for recognition and morphological analysis of isolated astrocytes in phase contrast microscopy

Scientific Reports
Astrocytes are glycolytically active cells in the central nervous system playing a crucial role in various brain processes from homeostasis to neurotransmission.
Egor V. Yakovlev, Ivan V. Simkin, Anastasiya A. Shirokova, Nataliya A. Kolotieva, Svetlana V. Novikova, Artur D. Nasyrov, Ilya R. Denisenko, Konstantin D. Gursky, Ivan N. Shishkov, Diana E. Narzaeva, Alla B. Salmina, Stanislav O. Yurchenko, Nikita P. Kryuchkov   +12 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A four-channel microfluidic model of the blood–brain and blood–cerebrospinal fluid barriers: fluid dynamics analysis

Micro and Nano Systems Letters
Brain-on-a-chip is an emerging field involving microfluidic devices capable of mimicking the structure and function of the human brain. Existing research often focuses on single barriers, such as the blood–brain barrier or blood–cerebrospinal fluid ...
Pavel A. Libet, Leonid Y. Polynkin, Mikis R. Saridis, Egor V. Yakovlev, Sofia A. Korsakova, Alla B. Salmina, Anton S. Averchuk, Natalia A. Rozanova, Stanislav O. Yurchenko   +8 more
doaj   +1 more source