Results 71 to 80 of about 4,927 (252)

Neuroichthyosis With a De Novo Variant c.494C>T in ELOVL1 and Severe Pruritus Relieved by Dupilumab

Pediatric Dermatology, Volume 42, Issue 4, Page 844-848, July/August 2025.
ABSTRACT We report a patient with neuroichthyosis with an ELOVL1 variant associated with severe pruritus who responded well to dupilumab therapy. Our case is the third known patient reported with this de novo heterozygous dominant variant. The feature of severe progressive pruritus greatly impairing quality of life is unique among these reports.
Danielle Marcoux, Sophie‐Anne Savard, Victor Kokta, Elsa Rossignol, Luis H. Ospina   +4 more
wiley   +1 more source

Fluocinolone acetonide and its potential in the treatment of chronic diabetic macular edema

Clinical Ophthalmology, 2013
Christos Haritoglou, Aljoscha S Neubauer, Marcus KerntDepartment of Ophthalmology, Ludwig-Maximilians-University, Munich, GermanyAbstract: Diabetic macular edema (DME) is a potentially sight-threatening disease that predominantly affects patients with ...
Haritoglou C, Neubauer AS, Kernt M
doaj  

Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide

Drug Development and Industrial Pharmacy, 2021
The rabble-rousing skin condition can be conventionally treated, but due to some demerits, there is a need to find a novel approach with an appropriate release profile. The research work narrates the optimization of the topical delivery system of Fluocinolone acetonide loaded in pluronic lecithin organogel. The preliminary studies were carried out and,
Dinal Patel, Viral Patel
openaire   +4 more sources

Expert Consensus on the Clinical Application of PI3K/AKT/mTOR Inhibitors in the Treatment of Breast Cancer (2025 Edition)

Cancer Innovation, Volume 4, Issue 3, June 2025.
ABSTRACT Background The phosphoinositide 3‐kinase (PI3K)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway (PAM pathway) plays a critical role in breast cancer pathogenesis and progression, and is closely linked with resistance to endocrine therapy in advanced breast cancer.
The Breast Cancer Expert Committee of the National Quality Control Center for Cancer, The Expert Committee on Cancer Prevention and Treatment of the Health China Research Center, The Society of Clinical Research on Oncology Medications of the China Anti‐Cancer Association, The Society of Onco‐Pathology of the China Anti‐Cancer Association   +3 more
wiley   +1 more source

Evaluating the Safety, Efficacy and Patient Acceptability of Intravitreal Fluocinolone Acetonide (0.2mcg/Day) Implant in the Treatment of Non-Infectious Uveitis Affecting the Posterior Segment

Clinical Ophthalmology, 2021
Laura R Steeples,1,2 Sasa Pockar,1 Nicholas P Jones,1,2 Inês Leal3,4 1Manchester Royal Eye Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; 2Faculty of Biology, Medicine &
Steeples LR, Pockar S, Jones NP, Leal I
doaj  

Anti-Inflammatory Effect of Dexamethasone Controlled Released From Anterior Suprachoroidal Polyurethane Implants on Endotoxin-Induced Uveitis in Rats. [PDF]

, 2016
Targeted drug delivery to the ocular tissues remains a challenge. Biodegradable intraocular implants allow prolonged controlled release of drugs directly into the eye. In this study, we evaluated an anterior suprachoroidal polyurethane implant containing
Ayres, E., Barbosa Saliba, J., Behar-Cohen, F., Bousquet, E., Fernandes-Cunha, G.M., Kowalczuk, L., Ligório Fialho, S., Naud, M.C., Oréfice, R.L., Rodrigues Da Silva, G., Silva-Cunha, A., Tekaya, M., Vieira, L., Zhao, M.   +13 more
core   +2 more sources

Fluocinolone acetonide topical oil for scalp psoriasis

Journal of Dermatological Treatment, 2004
Numerous preparations that are available for the treatment of psoriasis of the scalp contain high potency steroids, such as betamethasone dipropionate lotion or clobetasol propionate solution. Of special interest is a currently marketed oil preparation that contains the steroid fluocinolone acetonide (0.01%), classified as low potency (Class 6) steroid.
H Mendelsohn, M Pugliese, Howard I. Maibach, N. J. Lowe, M Pauporte, DJ Friedman, I Cargill, R.G. Ramirez   +7 more
openaire   +3 more sources

Off‐Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives

Experimental Dermatology, Volume 34, Issue 4, April 2025.
ABSTRACT JAK inhibitors are used to treat various inflammatory skin diseases. However, systemic formulations are associated with an increased risk of major adverse events. Ruxolitinib 1.5% cream is a selective topical JAK1 and JAK2 inhibitor, which has recently been approved by EMA and MHRA for treating non‐segmental vitiligo, while being FDA‐approved ...
Marco Spadafora, Serena Morsia, Vito Giuseppe Di Lernia, Shaniko Kaleci, Giovanni Pellacani, Caterina Longo   +5 more
wiley   +1 more source

Treatment of recurrent aphthous stomatitis. A literature review [PDF]

, 2014
Recurrent aphthous stomatitis (RAS) is the most common chronic disease of the oral cavity, affecting 5-25% of the population. The underlying etiology remains unclear, and no curative treatment is available.
Belenguer Guallar, Irene, Claramunt Lozano, Ariadna, Jiménez Soriano, Yolanda   +2 more
core   +4 more sources

Fluocinolone acetonide intravitreal implant for the treatment of diabetic macular edema

Drug Design, Development and Therapy, 2013
Wyatt B Messenger, Robert M Beardsle, Christina J FlaxelCasey Eye Institute, Oregon Health and Science University, Portland, OR, USAAbstract: Diabetic macular edema (DME) remains one of the leading causes of moderate to severe vision loss. Although laser
Messenger WB, Beardsley RM, Flaxel CJ
doaj