Mifepristone, a blocker of glucocorticoid receptors, promotes photoreceptor death [PDF]
PURPOSE: Glucocorticoids are best known by their protective effect on retinal photoreceptor damage. However, they could also be involved in photoreceptor homeostasis under basal, nonstressful conditions.
Bachor, Tomás Pedro +4 more
core +1 more source
Keratoprosthesis, silicone oil placement, and fluocinolone acetonide implant for treatment of uveitis-associated hypotony and keratopathy [PDF]
Arman Mosenia +3 more
openalex +1 more source
ABSTRACT JAK inhibitors are used to treat various inflammatory skin diseases. However, systemic formulations are associated with an increased risk of major adverse events. Ruxolitinib 1.5% cream is a selective topical JAK1 and JAK2 inhibitor, which has recently been approved by EMA and MHRA for treating non‐segmental vitiligo, while being FDA‐approved ...
Marco Spadafora +5 more
wiley +1 more source
Liu QY, He MM, Shi H, et al. Drug Des Devel Ther. 2015;9: 2527–2535. In “Efficacy and safety of different doses of a slow release corticosteroid implant for macular edema: meta-analysis of randomized controlled trials” published ...
Liu QY +8 more
doaj
Treatment of Solar Lentigines: A Systematic Review of Clinical Trials
ABSTRACT Background Solar lentigines, resulting from chronic UV exposure, are early signs of photoaging and can significantly affect individuals. Aims This systematic review evaluates the efficacy, safety, and tolerability of treatments for solar lentigines in light of a lack of conclusive evidence regarding optimal therapy options.
Ghazal Mardani +4 more
wiley +1 more source
Ophthalmic Inserts prepared either by Extrusion or by Freeze-Drying : Technological and Biopharmaceutical Characterization [PDF]
The main goal of this thesis is the development of an ophthalmic biodegradable insert containing fluocinolone acetonide (FA), to apply in the posterior segment of the eye. The inserts under study were prepared using the hot-melt extrusion technique (HME).
TERRENI, ELEONORA
core
Topical Tocopherol for treatment of reticular oral lichen planus: randomized, double-blind, crossover study [PDF]
This randomized, double-blind, placebo-controlled crossover study assessed the efficacy of topical tocopherol acetate compared with placebo in easing oral discomfort in patients with reticular oral lichen planus (ROLP)
Bacci, Christian +5 more
core +1 more source
Melasma Management: A Comprehensive Review of Treatment Strategies Including BTX‐A
ABSTRACT Background Botulinum toxin A (BTX‐A) is a widely utilized protein derived from the bacterium Clostridium botulinum, known for its effectiveness in treating various medical conditions involving muscle spasticity, involuntary muscle movements, and pain disorders.
Barbara Kania +2 more
wiley +1 more source
Follow-up study of over three years of patients with uveitis after cataract phacoemulsification: outcomes and complications [PDF]
Purpose: To evaluate the rate and onset of intraoperative and postoperative complications post-phacoemulsification. Methods: One hundred sixty-two eyes of 145 patients with uveitis who underwent phacoemulsification between 2006 and 2009 were identified
ABBOUDA, ALESSANDRO +5 more
core +1 more source
Clinical Trials Conducted on Herbal Remedies for the Treatment of Melasma: A Scoping Review
ABSTRACT Introduction Melasma, also known as chloasma, is a common skin disorder characterized by acquired hyperpigmentation. Many patients with this condition prefer using herbal remedies instead of chemical agents. This study aims to review clinical trials conducted on the effectiveness of herbal remedies in treating melasma.
Mohammad Mahdi Parvizi +5 more
wiley +1 more source

