Results 71 to 80 of about 1,816 (199)

Corticosteroids for diabetic macular edema

Taiwan Journal of Ophthalmology, 2019
Diabetic macular edema (DME) is a chronic condition with a multifactorial pathogenesis. Vascular endothelial growth factor (VEGF) and several inflammatory mediators are upregulated in eyes with DME.
Jorge Chawan-Saad, Max Wu, Andres Wu, Lihteh Wu   +3 more
doaj   +1 more source

Elevated Intraocular Pressure After Intravitreal Steroid Injection in Diabetic Macular Edema: Monitoring and Management [PDF]

, 2016
INTRODUCTION: With the increasing use of intravitreal administration of corticosteroids in macular edema, steroid-induced intraocular pressure (IOP) rise is becoming an emergent issue.
Denis, P, Diestelhorst, M, Figueiredo, AR, Garway-Heath, DF, Goñi, FJ, Nordmann, J-P, Stalmans, I, Taylor, S   +7 more
core  

Management of pediatric uveitis [PDF]

, 2014
Pediatric uveitis is a topic of special interest not only because of the unique diagnostic and therapeutic challenges but also because of the lifetime burden of vision loss if the problem is not adequately treated, as well as the economic and ...
Foster, C. Stephen, Freitas-Neto, Clovis A., Wentworth, Bailey A.   +2 more
core   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Recent Investigations on Pathogenesis, Biomarkers, Epigenetics, and Emerging Therapeutic Strategies to Modulate Multiple Signaling Pathways in Diabetic Retinopathy

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Background Diabetic retinopathy (DR) is a progressive microvascular complication related to diabetes mellitus and remains a profound cause of vision impairment and blindness globally. In addition to its ocular manifestations, DR is increasingly recognized as a main risk factor for systemic diseases, including cardiovascular and neurodegenerative ...
Zixuan Huang, Jing Wei, Dayong Yang, Kofi Asiedu   +3 more
wiley   +1 more source

Oxidative Stress and Microvascular Alterations in Diabetic Retinopathy: Future Therapies

Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019
Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin. However, patients’ metabolic control is inadequate in a high percentage of them and a major cause of chronic diseases like diabetic retinopathy. Approximately 15% of patients have some degree of diabetic retinopathy when diabetes is first diagnosed, and most will ...
María L. Rodríguez, Salvador Pérez, Salvador Mena-Mollá, M. Carmen Desco, Ángel Luis Ortega, Christopher Horst Lillig   +5 more
wiley   +1 more source

Treatment of steroid-induced elevated intraocular pressure with anecortave acetate: a randomized clinical trial. [PDF]

, 2012
PURPOSE: The present study is the first randomized clinical trial designed to evaluate the intraocular pressure (IOP)-lowering effect of anecortave acetate (AA) administered at 3 doses (3, 15, or 30 mg) as an anterior juxtascleral depot (AJD) in patients
Bergamini, Michael V. W., Callanan, David G., Dickerson, Jaime E., Dirks, Monte S., Landry, Theresa A., Moster, Marlene R., Robin, Alan L., Scheib, Sally A., Stalmans, Ingeborg, Van Calster, Joachim   +9 more
core   +2 more sources

Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease

Responsive Materials, Volume 3, Issue 4, November 2025.
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang, Jiayi Hou, Yameng Zhao, Yiwen Wang, Kexin Wang, Siyu Li, Yange Wang, Jiehao Zhang, Shenao Ding, Chenxu Zhang, Zongming Song, Ye Tao   +11 more
wiley   +1 more source

Evaluating the Safety, Efficacy and Patient Acceptability of Intravitreal Fluocinolone Acetonide (0.2mcg/Day) Implant in the Treatment of Non-Infectious Uveitis Affecting the Posterior Segment

Clinical Ophthalmology, 2021
Laura R Steeples,1,2 Sasa Pockar,1 Nicholas P Jones,1,2 Inês Leal3,4 1Manchester Royal Eye Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK; 2Faculty of Biology, Medicine &
Steeples LR, Pockar S, Jones NP, Leal I
doaj  

A review on polymers in ocular drug delivery systems

MedComm – Biomaterials and Applications, Volume 3, Issue 2, June 2024.
Polymers play a pivotal role in ocular drug delivery, revolutionizing treatment approaches. These biomaterials enable controlled and sustained drug release at the targeted site, enhancing bioavailability and patient compliance. From nanosized particle‐based formulations to in situ gelation mechanisms, polymers offer improved treatment options for a ...
Amol C. Bisen, Arpon Biswas, Ayush Dubey, Sachin N. Sanap, Sristi Agrawal, Karan S. Yadav, Vaishali Singh, Priyanka Rawat, Sudhanshu Sagar, Madhav N. Mugale, Rabi S. Bhatta   +10 more
wiley   +1 more source