Results 261 to 270 of about 503,914 (338)

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

open access: yesAdvanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura   +7 more
wiley   +1 more source

High-throughput assay for measuring target occupancy of covalent compounds: a case study with MK2. [PDF]

open access: yesRSC Chem Biol
Wong JL   +13 more
europepmc   +1 more source

Optofluidic Raman Analysis and Capacity Recovery in Li‐ion Cells

open access: yesAdvanced Materials Technologies, EarlyView.
Operando Raman spectroscopy is used to monitor the degradation of commercial Li‐ion cells. Using a microfluidic access port, small amounts of electrolyte are sampled into a hollow‐core optical fibre, where fibre‐enhanced Raman analysis reveals Li+ solvation changes and solvent evolution.
Ermanno Miele   +9 more
wiley   +1 more source

Rodent Enteric Glia Culture. [PDF]

open access: yesMethods Mol Biol
Gonzales J, Durand T, Gulbransen BD.
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto   +6 more
wiley   +1 more source

Generation and characterization of human induced pluripotent stem cells from neuropathologically confirmed multiple system atrophy patient-derived fibroblasts. [PDF]

open access: yesFront Immunol
Alemany-Ribes M   +15 more
europepmc   +1 more source

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