A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. [PDF]
PLoS ONE, 2015 Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization.
Sindy Liao-Chan +8 more
doaj +1 more source
HUBUNGAN PERILAKU VULVA HYGIENE DENGAN KEJADIAN FLUOR ALBUS PADA REMAJA PUTRI DI SMA UNGGULAN AMANATUL UMMAH SURABAYA [PDF]
, 2017 Perilaku kesehatan reproduksi yang kurang masih banyak ditemukan pada remaja putri, terutama dalam menjaga kesehatan organ reproduksi serta pemahaman yang kurang akan vulva hygiene seperti perilaku cebok yang kurang benar ...
SAADAH, HANIFATUS
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Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]
, 2013 The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Heilemann, Mike +4 more
core +3 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Cleaner Chemical EngineeringThe most useful physical solvents in the industry are Propylene Carbonate (Fluor SolventSM), Methanol (Rectisol), Dimethyl Ether of Polyethylene Glycol (DEPG - Selexol) and Sulfolane.
Mohsen Abbaszadeh
doaj +1 more source
Hubungan Antara Tingkat Pengetahuan Remaja Putri Mengenai Kebersihan Genitalia Eksterna dan Kejadian Keputihan di SMA Negeri 1 Sukodono [PDF]
, 2015 Background: Fluor albus a reproductive health problems most commonly occur in women. More than 75% of women in the world have experienced fluor albus. Knowledge and care unfavorable external genitalia can lead to problems in the reproductive organs such ...
, dr. Dodik Nursanto +2 more
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3D bioprinted human cortical neural constructs derived from induced pluripotent stem cells [PDF]
, 2019 Bioprinting techniques use bioinks made of biocompatible non-living materials and cells to build 3D constructs in a controlled manner and with micrometric resolution.
Benedetti, Maria Cristina +9 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
HUBUNGAN ANTARA STRES PSIKIS MENJELANG UAN DAN SNMPTN DENGAN KEJADIAN FLUOR ALBUS PADA SISWI SMA PESERTA BIMBINGAN BELAJAR [PDF]
, 2013 Jeanne Fransisca, G0010106, 2013. Hubungan antara Stres Psikis Menjelang UAN dan SNMPTN dengan Kejadian Fluor Albus pada Siswi SMA Peserta Bimbingan Belajar. Skripsi. Fakultas Kedokteran Universitas Sebelas Maret Surakarta.
Fransisca, Jeanne
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