Results 51 to 60 of about 488,008 (284)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Quantitative assessment of antibody internalization with novel monoclonal antibodies against Alexa fluorophores. [PDF]
PLoS ONE, 2015 Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization.
Sindy Liao-Chan +8 more
doaj +1 more source
GAMBARAN TINGKAT PENGETAHUAN TENTANG FLUOR ALBUS PADA MAHASISWI SEMESTER VI DI UNIVERSITAS NEGERI SURABAYA [PDF]
, 2012 Fluor albus merupakan salah satu masalah yang sejak lama ada pada kaum wanita dan seringkali tidak ditangani serius khususnya pada remaja. Padahal, Fluor albus biasa jadi indikasi adanya penyakit.
AL-HABSYI, ALVIN
core
Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]
, 2013 Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América +5 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
HUBUNGAN POLA STRUKTUR PRISMA DAN KONSENTRASI FLUOR PADA PERMUKAAN EMAIL SETELAH PAPARAN KOPI DAN TEH [PDF]
, 2016 ABSTRAKNama: Rini MaulidaProgram Studi: Kedokteran GigiJudul Skripsi: Hubungan Pola Struktur Prisma dan Konsentrasi Fluor Pada Permukaan Email setelah Paparan Kopi dan TehKopi dan teh sering dikonsumsi oleh masyarakat Indonesia dan Aceh. Berdasarkan
RINI MAULIDA
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells [PDF]
, 2019 In this work, we have exploited the unique properties of a chimeric archaeal-human ferritin to encapsulate, deliver and release cytochrome c and induce apoptosis in a myeloid leukemia cell line.
Baiocco, P. +8 more
core +2 more sources
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source