Results 91 to 100 of about 262,034 (273)

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

open access: yesAdvanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll   +16 more
wiley   +1 more source

Water-filtered infrared-A (wIRA) can act as a penetration enhancer for topically applied substances

open access: yesGMS German Medical Science, 2008
Background: Water-filtered infrared-A (wIRA) irradiation has been shown to enhance penetration of clinically used topically applied substances in humans through investigation of functional effects of penetrated substances like vasoconstriction by ...
Sterry, Wolfram   +7 more
doaj  

Computationally Efficient Optic Nerve Head Detection in Retinal Fundus Images [PDF]

open access: yesBiomedical Signal Processing and Control Volume 11, May 2014, 2019
This paper presents a computationally efficient method for the detection of optic nerve head in both color fundus and fluorescein angiography images. It involves a combination of Radon transformation and multi-overlapping windows within an optimization framework in order to achieve a robust detection in the presence of various structural, color, and ...
arxiv  

Upconversion Nanoparticle‐Covalent Organic Framework Core–shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging

open access: yesAdvanced Materials, EarlyView.
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim   +8 more
wiley   +1 more source

A comparison of NCT, Goldman application tonometry values with and without fluorescein

open access: yesClinical Ophthalmology, 2018
Hakika Erdogan, Ziya Akingol, Ozlem Cam, Sadik Sencan Department of Ophthalmology, Faculty of Medicine, Maltepe University, Maltepe, Istanbul, Turkey  Purpose: The aim of the study was to statistically compare intraocular pressure (IOP) values ...
Erdogan H, Akingol Z, Cam O, Sencan S
doaj  

Fluorescein-containing amphiphilic copolymers as promising objects for biomedical research

open access: yesБіологічні студії
Background. Polymeric nanoparticles are increasingly used as drug carriers. They demonstrate a significant improvement in the therapeutic efficacy of drugs and are widely studied as components of drug transport and release systems.
Maria Yakoviv   +6 more
doaj   +1 more source

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