Results 241 to 250 of about 481,368 (398)

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

Rapid mapping of spinal and supraspinal connectome via self-targeting glucose-based carbon dots.

Nanoscale
Seven YB, Seven ES, Kirbas Cilingir E, Parikh K, Aydin M, Luca EK, Nair J, Leblanc RM.   +7 more
europepmc   +1 more source

Fluorescence-Guided Surgery for Gliomas: Past, Present, and Future. [PDF]

Cancers (Basel)
Rodriguez B, Brown CS, Colan JA, Zhang JY, Huq S, Rivera D, Young T, Williams T, Subramaniam V, Hadjipanayis C.   +9 more
europepmc   +1 more source

Compressed Cells Facilitate Adhesion Through Glycocalyx

Advanced Science, EarlyView.
This study quantifies how cell compression and confinement triggers cell adhesion. Under low compression, integrins dominate cell adhesion to extracellular matrix (ECM) proteins, whereas the glycocalyx contributes weak unspecific adhesion. With increasing compression, the glycocalyx increases its unspecific adhesion to ECM and non‐ECM proteins and can ...
Xiaole Wang, Jonne Helenius, Daniel J. Müller, Nico Strohmeyer   +3 more
wiley   +1 more source

Case Report: A rare presentation of short posterior ciliary artery occlusion with paracentral acute middle maculopathy. [PDF]

Front Med (Lausanne)
Yuanmin D, Jiehui X.
europepmc   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Influence of Immune Cells on Corneal Nerve Morphological Analysis and Clinical Relevance in Diabetes-Related Dry Eye. [PDF]

Transl Vis Sci Technol
Ma B, Li H, Wang Y, Li W, Mou L, Liu Y, Liu R, Zheng Y, Liu X, Zhao Y, Qi H.   +10 more
europepmc   +1 more source

WSGC@FA@PEG/PEI‐SPIONs Mitigate Chemoresistance in Gastric Adenocarcinoma by Modulating the Notch Signaling Pathway and Mitophagy

Advanced Science, EarlyView.
WSGC peptide reverses drug resistance in GA by modulating the Notch signaling pathway and mitophagy at the molecular level. Abstract This study investigates the molecular mechanisms by which superparamagnetic iron oxide nanoparticles (SPIONs) loaded with the WSGC peptide (WSGC@FA@PEG/PEI‐SPIONs)—a 40‐amino acid polypeptide derived from apoC‐III ...
Dongjian Song, Qiuliang Liu, Zechen Yan, Qi Wang, Meng Su, Hui Zhang, Longyan Shi, Yingzhong Fan, Qian Zhang, Heying Yang, Da Zhang   +10 more
wiley   +1 more source

The use of trypan blue to distinguish Pseudo-Seidel sign from lacrimal ductule versus glaucoma drainage device leakage. [PDF]

Am J Ophthalmol Case Rep
Mahmud H, Mesfin Y, Liu Y, Ou Y, Lu JE.
europepmc   +1 more source

Systemic Lipopolysaccharide Compromises the Blood-Labyrinth Barrier and Increases Entry of Serum Fluorescein into the Perilymph

Journal of the Association for Research in Otolaryngology, 2014
K. Hirose, J. Hartsock, Shane B. Johnson, P. Santi, A. Salt   +4 more
semanticscholar   +1 more source