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Fluorescein Derivatives as Fluorescent Probes for pH Monitoring along Recent Biological Applications

International Journal of Molecular Sciences, 2020
Potential of hydrogen (pH) is one of the most relevant parameters characterizing aqueous solutions. In biology, pH is intrinsically linked to cellular life since all metabolic pathways are implicated into ionic flows.
Florent Le Guern, Anne Gaucher, Martin Rottman   +2 more
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Unraveling the Mechanism for Tuning the Fluorescence of Fluorescein Derivatives: The Role of the Conical Intersection and nπ* State.

Journal of Physical Chemistry Letters, 2021
Although a large number of fluorescein derivatives have been developed and applied in many different fields, the general mechanisms for tuning the fluorescence of fluorescein derivatives still remain uncovered.
P. Zhou, Zhe Tang, Peng Li, Jianyong Liu
semanticscholar   +1 more source

Study of fluorescein glucuronide [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 1986
Comparative studies of fluorescein and fluorescein glucuronide were carried out. Binding to human serum protein was studied using an Amicon MPS-3 ultrafiltration unit; it averaged 63% for fluorescein glucuronide and 85% for fluorescein. Intracameral penetration of both compounds was studied in the human eye, and the concentration changes of both ...
Takase M, Makoto Araie, Seto C
openaire   +2 more sources

Fluorescein and fluorescein glucuronide in plasma

Acta Ophthalmologica, 1992
AbstractThe evaluation of the blood‐ocular barrier for fluorescein requires the measurement of free and unconjugated fluorescein in plasma. This study introduces a new and simple method for the determination of free fluorescein in plasma on the basis of determined total free plasma fluorescense and the free fraction of fluorescence.
Thomas Olsen, Folmer Nielsen-Kudsk, Lars Loumann Knudsen   +2 more
openaire   +3 more sources

Utility of sodium fluorescein for achieving resection targets in glioblastoma: increased gross- or near-total resections and prolonged survival.

Journal of Neurosurgery, 2020
OBJECTIVEIt is commonly reported that achieving gross-total resection of contrast-enhancing areas in patients with glioblastoma (GBM) improves overall survival.
G. Katsevman, R. Turner, Ogaga Urhie, J. L. Voelker, S. Bhatia   +4 more
semanticscholar   +1 more source

Fluorescein and fluorescein glucuronide in plasma after intravenous injection of fluorescein

Acta Ophthalmologica, 1988
Abstract.After intravenous injection of fluorescein the time‐course of the plasma concentrations of fluorescein (F) and fluorescein glucuronide (FG) was studied in 18 insulin‐dependent diabetics with various degrees of nephropathy, and in two non‐diabetic subjects.
Eva Hommel, Michael Larsen, S. Loft, Henrik Lund-Andersen   +3 more
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Comparison of 5-aminolevulinic acid and sodium fluorescein for intraoperative tumor visualization in patients with high-grade gliomas: a single-center retrospective study.

Journal of Neurosurgery, 2020
OBJECTIVE Maximal safe resection is an important surgical goal in the treatment for high-grade gliomas. Fluorescent dyes help the surgeon to distinguish malignant tissue from healthy.
R. W. Hansen, C. B. Pedersen, Bo Halle, A. Korshoej, M. Schulz, B. Kristensen, F. Poulsen   +6 more
semanticscholar   +1 more source

Prevalence of anastomotic leak and the impact of indocyanine green fluorescein imaging for evaluating blood flow in the gastric conduit following esophageal cancer surgery

Esophagus, 2017
Backgrounds and aimAnastomotic leak (AL) following esophagectomy for esophageal cancer (EC) remains an important cause of prolonged hospitalization and impaired quality of life.
M. Ohi, Y. Toiyama, Y. Mohri, S. Saigusa, Takashi Ichikawa, Tadanobu Shimura, H. Yasuda, Y. Okita, S. Yoshiyama, Minako Kobayashi, T. Araki, Y. Inoue, M. Kusunoki   +12 more
exaly   +2 more sources

Labeling of Oligonucleotides with Fluorescein

Molecular Biotechnology, 1997
The labeling of oligonucleotide probes using a fluorescein-labeled nucleotide is described. The reaction is characterized by careful control of the nucleotide and probe molar ratio in order to produce a tail that gives good detection sensitivity without compromising hybridization stringency control of the probe sequence.
Patricia M. E. Chadwick, Ian Durrant
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