Results 1 to 10 of about 746 (115)

Forward Light Scattering of First to Third Generation Vitreous Body Replacement Hydrogels after Surgical Application Compared to Conventional Silicone Oils and Vitreous Body

open access: yesGels, 2023
To treat certain vitreoretinal diseases, the vitreous body, a hydrogel composed of mostly collagen and hyaluronic acid, must be removed. After vitrectomy surgery, the vitreous cavity is filled with an endotamponade.
Maximilian Hammer   +8 more
doaj   +3 more sources

LC-MS/MS Analysis Elucidates a Daily Rhythm in Orexin A Concentration in the Rat Vitreous Body

open access: yesMolecules, 2021
Orexins are two neuropeptides synthesised mainly in the brain lateral hypothalamic area. The orexinergic system provides arousal-dependent cues for a plethora of brain centres, playing a vital role in feeding behaviour, regulation of the sleep–wake cycle
Lukasz Chrobok   +3 more
doaj   +3 more sources

Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body

open access: yesPharmaceutics, 2022
Silicone oil endotamponades provide a reservoir for drugs in the eye. Following vitrectomy surgery to treat retinal detachments, extensive diabetic retinopathy or endophthalmitis, they can be used as long-term lipophilic depots.
Maximilian Hammer   +7 more
doaj   +3 more sources

An Inverse Method to Determine Mechanical Parameters of Porcine Vitreous Bodies Based on the Indentation Test

open access: yesBioengineering, 2023
The vitreous body keeps the lens and retina in place and protects these tissues from physical insults. Existing studies have reported that the mechanical properties of vitreous body varied after liquefaction, suggesting mechanical properties could be ...
Haicheng Zu   +3 more
doaj   +1 more source

Mathematical modeling of fluid movement inside the eyeball during intravitreal injection

open access: yesРоссийский офтальмологический журнал, 2022
Intravitreal injections show an avalanche-like growth the world over.   Purposes: 1) create a mathematical model of the eyeball and fluid movement inside the eye, assuming the simplified structure of the vitreous body (without tanks); 2) estimate the ...
D. V. Lipatov   +4 more
doaj   +1 more source

Vitreous substitutes:challenges and directions [PDF]

open access: yesInternational Journal of Ophthalmology, 2015
Thenatural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels,
Qian-Ying Gao, Yue Fu, Yan-Nian Hui
doaj   +1 more source

Assessing the density of the vitreous body in young people with type I diabetes using multispiral computer tomography

open access: yesРоссийский офтальмологический журнал, 2022
Diabetic retinopathy (DR) is one of the severe complications of diabetes mellitus (DM). Despite the multiyear research of DR pathogenesis, the role of the vitreous body in DR development has not been sufficiently studied.
N. M. Juldasheva, F. S. Tadzhieva
doaj   +1 more source

Vitreous function and intervention of it with vitrectomy and other modalities [PDF]

open access: yesInternational Journal of Ophthalmology, 2022
The vitreous body, the largest intraocular component, plays a key role in eye development, refraction, cell barrier function, oxygen metabolism and the pathogenesis of assorted diseases.
Yao Zong, Qian-Ying Gao, Yan-Nian Hui
doaj   +1 more source

[RETRACTED]Vitreous function and intervention of it with vitrectomy and other modalities [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
[RETRACTED]The vitreous body, the largest intraocular component, plays a key role in eye development, refraction, cell barrier function, oxygen metabolism and the pathogenesis of assorted diseases. Age, refraction and systemic diseases can cause vitreous
Yao Zong, Qian-Ying Gao, Yan-Nian Hui
doaj   +1 more source

Ex Vivo Visualization of Distribution of Intravitreal Injections in the Porcine Vitreous and Hydrogels Simulating the Vitreous

open access: yesPharmaceutics, 2023
The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations
Tobias Auel   +6 more
doaj   +1 more source

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