Results 51 to 60 of about 496,070 (334)

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores.

Journal of Biological Chemistry, 1989
A new group of fluorescent indicators with visible excitation and emission wavelengths has been synthesized for measurements of cytosolic free Ca2+. The five compounds, "rhod-1," "rhod-2," "fluo-1," "fluo-2," and "fluo-3" (Figs.
A. Minta, J. Kao, R. Tsien
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Cine recording ophthalmoscope [PDF]

, 1972
Camera system provides accurate photographic recording during acceleration of centrifuge and permits immediate observation of dynamic changes in retinal circulation by a closed-circuit television loop. System consists of main camera, remote control unit,
Fitzgerald, J. W.
core   +1 more source

EVALUATION OF THE ANTIOXIDANT ACTIVITY OF THE FLAVONOIDS ISOLATED FROM HELIOTROPIUM SINUATUM RESIN USING ORACFL, DPPH AND ESR METHODOLOGIES [PDF]

, 2016
Indexación: Web of Science; Scielo.The antioxidant capacity has been determined for a number of flavonoid compounds from Heliotropium sinuatum, a plant that grows in arid areas in the north of Chile.
Barriga-Gonzalez, G, Chamorro, E, Modak, B, Olea-Azar, C, Salinas, M   +4 more
core   +1 more source

Prevalence of anastomotic leak and the impact of indocyanine green fluorescein imaging for evaluating blood flow in the gastric conduit following esophageal cancer surgery

Esophagus, 2017
Backgrounds and aimAnastomotic leak (AL) following esophagectomy for esophageal cancer (EC) remains an important cause of prolonged hospitalization and impaired quality of life.
M. Ohi, Y. Toiyama, Y. Mohri, S. Saigusa, Takashi Ichikawa, Tadanobu Shimura, H. Yasuda, Y. Okita, S. Yoshiyama, Minako Kobayashi, T. Araki, Y. Inoue, M. Kusunoki   +12 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Synthetic strategies for the fluorescent labeling of epichlorohydrin-branched cyclodextrin polymers

Beilstein Journal of Organic Chemistry, 2014
The fluorescent tagging of cyclodextrin derivatives enlarges their spectroscopic properties thus generating chemosensors, biological tools for visualization and sophisticated photoresponsive devices.
Milo Malanga, Mihály Bálint, István Puskás, Kata Tuza, Tamás Sohajda, László Jicsinszky, Lajos Szente, Éva Fenyvesi   +7 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Resection of gliomas by intraoperative high⁃field MRI combined with fluorescence⁃ guided

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To investigate the efficacy and safety of intraoperative high⁃field MRI combined with fluorescence⁃guided glioma resection. Methods A total of 53 patients with glioma admitted to The Fisrt Bethune Hospital of Jilin University from June 2017 to ...
DONG Ze⁃ping, ZHAO Yang, CHEN Fan, LI Wen⁃zhong, CHEN Da⁃wei   +4 more
doaj   +1 more source

Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns [PDF]

, 2012
Pyrrole–imidazole (Py–Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein–DNA interactions and modulating gene expression in living cells.
Baird, Belitsky, Best, Bijsterbosch, Bradford, Chenoweth, Chenoweth, Chenoweth, Cleutjens, Cohen, Crowley, David C. Montgomery, Dervan, Dervan, Dickinson, Dose, D’Adamio, Edelson, Edwards, Gissot, Herman, Hesselberth, Hsu, Hsu, Jacobs, Johnson, Jordan L. Meier, Krutzik, Kwon, Magee, Mapp, Matsuda, Meijsing, Mrksich, Muzikar, Nickols, Nickols, Nickols, Nishijima, Ohtsukia, Olenyuk, Peter B. Dervan, Poulin-Kerstien, Reddy, Riegman, Rucker, Schmidt, Schultz, So, Swalley, Tsai, Van Dyke, Vaquerizas, Vichai, Yao   +54 more
core   +2 more sources