Results 121 to 130 of about 1,649,089 (269)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Evaluating the peak-to-valley dose ratio of synchrotron microbeams using PRESAGE fluorescence [PDF]

, 2012
Nathan Annabell, Naoto Yagi, Keiji Umetani, C. W. Wong, Moshi Geso   +4 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Multimodal Phasor Approach to Study Breast Cancer Cell Invasion in a 3D Spheroid Model

Chemical & Biomedical Imaging
Giulia Tedeschi, Francesco Palomba, Lorenzo Scipioni, Michelle A. Digman   +3 more
doaj   +1 more source

Chlorophyll fluorescence imaging of cadmium-treated white cabbage plants [PDF]

, 2013
M. Borek, R. Bączek‐Kwinta, Marcin Rapacz   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Consecutive Moderate and Severe Drought Stresses Affect Chlorophyll Fluorescence and Non‐structural Carbohydrates Dynamics in Grapevine Leaves [PDF]

Monica Canton, Francesco Mirone, Franco Meggio, A Pichierri, Valentino Casolo, Giovanni Battista Tornielli, Andrea Pitacco   +6 more
openalex   +1 more source

Fluorescence Quenching and Energy Transfer in Monomolecular Films Containing Chlorophyll [PDF]

, 1964
A. G. Tweet, W. D. Bellamy, George L. Gaines   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Temperature-Controlled Fluorescence Fingerprint for Identifying Pseudo-nitzschia hasleana in Harmful Algal Blooms [PDF]

A. Yu. Popik, S. S. Voznesenskiy, Tatiana Dunkai, A.A. Leonov, T. Yu. Orlova   +4 more
openalex   +1 more source