Results 141 to 150 of about 2,746,497 (369)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Porous Silicon Bragg Reflector/Carbon Dot Hybrids: Synthesis, Nanostructure, and Optical Properties

Frontiers in Chemistry, 2018
Carbon dots (C-dots) exhibit unique fluorescence properties, mostly depending upon their physical environments. Here we investigate the optical properties and nanostructure of Carbon dots (C-dots) which are synthesized in situ within different porous ...
Naama Massad-Ivanir, Susanta Kumar Bhunia, Susanta Kumar Bhunia, Raz Jelinek, Raz Jelinek, Ester Segal, Ester Segal   +6 more
doaj   +1 more source

Fluorescence of Steroids. [PDF]

, 1956
Sven Arrhenius, Rainer Pesola, Karl-Gustav Paul, Hugo Theorell, B. Thorell   +4 more
openalex   +1 more source

On The Thermodynamics of Fluorescence [PDF]

Physical Review, 1918
n ...
openaire   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging microscopy (FLIM) data

Data in Brief, 2020
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1].
Zhen Liang, Jieqiong Lou, Lorenzo Scipioni, Enrico Gratton, Elizabeth Hinde   +4 more
doaj  

Temporal patterns in innate immunity parameters in reef‐building corals and linkages with local climatic conditions

Ecosphere, 2016
Extremes in seasonal environmental conditions can significantly impact the health and physiological functioning of reef corals, underscoring the need for knowledge of seasonally specific baselines from which to monitor and forecast impending stress ...
Jeroen A. J. M. van de Water, Joleah B. Lamb, Scott F. Heron, Madeleine J. H. van Oppen, Bette L. Willis   +4 more
doaj   +1 more source

Interpreting fluorescence detected 2D electronic spectroscopy [PDF]

arXiv, 2019
We explain current controversies regarding the interpretation of the cross peaks in the fluorescence detected coherent 2D spectroscopy.
arxiv  

Fluorescence of Fluorite and the Bivalent Europium Ion [PDF]

, 1935
Karl Przibram
openalex   +1 more source