Results 151 to 160 of about 1,475,531 (219)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The fluorescence-activating and absorption-shifting tag (FAST), a versatile protein marker for live plant cell imaging. [PDF]

Plant J
David P, Michaud M, Moyet L, Pullara S, Lacombe B, Zhu J, Gautier A, Desnos T, Bertrand E, Rolland N, Nussaume L.   +10 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Rational design of a fluorescent probe for the enantioselective and chemoselective recognition of chiral cysteine in wheat. [PDF]

Food Chem X
Yu X, Zeng C, Chen S, Liu Q, Fan C, Dong Q, Liang X, Chi W, Zeng C.   +8 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Intracellular logic computing with DNA tetrahedron processors enables precision cancer theranostics. [PDF]

Signal Transduct Target Ther
Gao Y, Wang Y, Qin Y, Zhang G, Gao S, Chen W, Yang S, Yang X, Tang Y, He Y, Lin Y, Willner I, Tian T, Cai X.   +13 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

MXene quantum dots for geochemical ion sensing: mechanism-driven design of integrated platforms. [PDF]

RSC Adv
Oriquat G, Mohammed Ali MS, Suleman AD, Shukla MB, M M R, Surya CP, Sharma P, Aldulaimi A, Noorizadeh H.   +8 more
europepmc   +1 more source