Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
Advanced Materials, EarlyView.Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic control enables cyclic switching between nanoscale groove and ridge states that modulates ligand accessibility of cellular integrins.
Hyunsik Hong +8 more
wiley +1 more source
Extending fluorescence anisotropy to large complexes using reversibly switchable proteins. [PDF]
Nat Biotechnol, 2023 Volpato A +7 more
europepmc +1 more source
Observation of ultra-high energy cosmic rays with the Telescope Array experiment
EPJ Web of Conferences, 2018 The origin of ultra-high energy cosmic rays (UHECRs) has been a longstanding mystery. The Telescope Array (TA) is the largest experiment in the northern hemisphere observing UHECR in Utah, USA. It aims to reveal the origin of UHECR by studying the energy
Takeishi Ryuji
doaj +1 more source
Towards monitoring conformational changes of the GPCR neurotensin receptor 1 by single-molecule FRET [PDF]
arXiv, 2018 Neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that is important for signaling in the brain and the gut. Its agonist ligand neurotensin (NTS), a 13-amino-acid peptide, binds with nanomolar affinity from the extracellular side to NTSR1 and induces conformational changes that trigger intracellular signaling processes.
arxiv
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source
Increasing insulin measurement throughput by fluorescence anisotropy imaging immunoassays. [PDF]
Anal Chim Acta, 2022 Wang Y, Adeoye DI, Wang YJ, Roper MG.
europepmc +1 more source
Ligand-induced oligomerization of the human GPCR neurotensin receptor 1 monitored in living HEK293T cells [PDF]
arXiv, 2019 The human neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that can be expressed in HEK293T cells by stable transfection. Its ligand is a 13-amino-acid peptide that binds with nanomolar affinity from the extracellular side to NTSR1. Ligand binding induces conformational changes that trigger the intracellular signaling processes.
arxiv
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
Probing Oxidant Effects on Superoxide Dismutase 1 Oligomeric States in Live Cells Using Single-Molecule Fluorescence Anisotropy. [PDF]
Chem Biomed Imaging, 2023 Chen H, Chen TY.
europepmc +1 more source
Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling
Advanced Materials, EarlyView.3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli +3 more
wiley +1 more source