Results 51 to 60 of about 984,356 (291)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Led induced chlorophyll fluorescence transient imager for measurements of health and stress status of whole plants [PDF]

, 2011
We have developed LED (light emitting diode) induced fluorescence transient imaging instrumentation to image the plant health/stress status by calculation of two images: Fv/Fm (variable fluorescence over saturation level of fluorescence) and the time ...
Jalink, H., Schoor, R., van der
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Unmixing for ultra-high-plex fluorescence imaging

Nature Communications, 2022
Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round.
Archibald Enninful, Alev Baysoy, Rong Fan   +2 more
doaj   +1 more source

Continuous volumetric imaging via an optical phase-locked ultrasound lens

, 2016
In vivo imaging at high spatiotemporal resolution is key to the understanding of complex biological systems. We integrated an optical phase-locked ultrasound lens into a two-photon fluorescence microscope and achieved microsecond-scale axial scanning ...
Cui, M., Germain, R., Kong, L., Lin, C., Little, J., Lämmermann, T., Tang, J., Yu, Y.   +7 more
core   +1 more source

An apertureless near-field microscope for fluorescence imaging [PDF]

, 2000
We describe an apertureless near field microscope for imaging fluorescent samples. Optical contrast is generated by exploiting fluorescent quenching near a metallized atomic force microscope tip.
Lessard, Guillaume A., Quake, Stephen R., Yang, T. J.   +2 more
core   +1 more source

Fluorescence lifetime imaging ophthalmoscopy

Progress in Retinal and Eye Research, 2017
Imaging techniques based on retinal autofluorescence have found broad applications in ophthalmology because they are extremely sensitive and noninvasive. Conventional fundus autofluorescence imaging measures fluorescence intensity of endogenous retinal fluorophores.
Chantal Dysli, Sebastian Wolf, Mikhail Y. Berezin, Lydia Sauer, Martin Hammer, Martin S. Zinkernagel   +5 more
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

easySTORM: a robust, lower-cost approach to localisation and TIRF microscopy [PDF]

, 2016
TIRF and STORM microscopy are super-resolving fluorescence imaging modalities for which current implementations on standard microscopes can present significant complexity and cost. We present a straightforward and low-cost approach to implement STORM and
Davies, T, Dunsby, C, French, PMW, Kwakwa, K, Munro, I, Neil, MAA, Parrinello, S, Purbhoo, MA, Savell, A   +8 more
core   +1 more source

Fluorescence imaging agents in cancerology [PDF]

Radiology and Oncology, 2010
One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection requests specific recognition. Tumor markers have to be ideally present on the surface of cancer cells. Their targeting with ligands coupled to imaging agents make them visible/detectable.Fluorescence imaging is ...
Bellard, Elisabeth, Ecochard, Vincent, Golzio, Muriel, Paganin-Gioanni, Aurélie, Paquereau, Laurent, Teissie, Justin   +5 more
openaire   +3 more sources