piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
Assessment of sperm chromosomal abnormalities using fluorescence in situ hybridization (FISH): implications for reproductive potential. [PDF]
Luongo FP+6 more
europepmc +1 more source
Application of Fluorescence In Situ Hybridization (FISH) in Oral Microbial Detection. [PDF]
Gu J+6 more
europepmc +1 more source
Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin+9 more
wiley +1 more source
Interlaboratory variability of HER2 fluorescence in situ hybridization testing in breast cancer: results of a multicenter proficiency-testing ring study in China. [PDF]
Peng R, Zhang K, Lin G, Li J.
europepmc +1 more source
False-Negative Testing for FIP1L1::PDGFRA by Fluorescence in situ Hybridization Is a Frequent Cause of Diagnostic Delay. [PDF]
Pongdee T+13 more
europepmc +1 more source
Phylogenetic Analysis of Methanogens in Sheep Rumen Ecosystem and Detection ofMethanomicrobium mobileby FluorescenceIn SituHybridization [PDF]
Kazuhiro Yanagita+5 more
openalex +1 more source
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang+11 more
wiley +1 more source
Use of high-resolution fluorescence in situ hybridization for fast and robust detection of SARS-CoV-2 RNAs. [PDF]
Hu J+8 more
europepmc +1 more source
FISH of Alu-PCR amplified YAC clones and applications in tumor cytogenetics [PDF]
Choo, K. H. A.+3 more
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