Results 281 to 290 of about 211,115 (326)
Some of the next articles are maybe not open access.
Fluorescent retinoid X receptor ligands for fluorescence polarization assay
Bioorganic & Medicinal Chemistry Letters, 2010Retinoid X receptor (RXR) agonists are candidate agents for the treatment of metabolic syndrome and type 2 diabetes via activation of peroxisome proliferator-activated receptor (PPAR)/RXR or liver X receptor (LXR)/RXR-heterodimers, which control lipid and glucose metabolism.
Shoya, Yamada +8 more
openaire +2 more sources
Fluorescence polarization applied to cellular microrheology
Biorheology, 1985The fluorescence polarization of probe molecules gives information on the “fluidity” of probe environment. Although the data cannot be related with absolute values of microviscosity, the method is largely used for probing the “fluidity” of lipid regions of biological membranes.
J F, Stoltz, M, Donner
openaire +2 more sources
Polarized fluorescence spectroscopy of human tissues
Optics Letters, 2002We report the results of a study carried out to investigate the effect of blood absorption on polarized and unpolarized fluorescence from resected tissue samples and tissue phantoms. The signatures of blood absorption were found to be significantly smaller in polarized fluorescence than in unpolarized fluorescence spectra.
N, Ghosh, S K, Majumder, P K, Gupta
openaire +2 more sources
Fluorescence polarization spectroscopy in protein analysis
The Analyst, 2003Information about concentration, molecular structure, binding events, and motion can be obtained using fluorescence spectroscopy methods. Fluorescence polarization spectroscopy is one such method, which studies the relationship between the polarization of light that is used for excitation and light that is subsequently detected from fluorescence.
Tina L, Mann, Ulrich J, Krull
openaire +2 more sources
Fluorescence polarization assay by flow cytometry
Journal of Immunological Methods, 1985Fluorescence polarization measurement on cell suspensions provides a highly sensitive means for detecting subtle changes in the cells, such as occur early after lymphocyte activation or on malignant transformation. We review here the principles of fluorescence polarization, its measurement by a commercially available flow cytometer and application of ...
J M, Rolland +4 more
openaire +2 more sources
Fluorescence Polarization: Past, Present and Future
Combinatorial Chemistry & High Throughput Screening, 2003Fluorescence polarization was first observed in 1920 and during the next few decades the theoretical foundations of the phenomenon were clearly established. In the last two decades of the 20(th) century, fluorescence polarization became one of the most prevalent methods used in clinical and biomedical sciences.
David M, Jameson, John C, Croney
openaire +2 more sources
Immunoassay methods based on fluorescence polarization
Talanta, 1989A review on the use of fluorescence polarization in immunoassay procedures is presented. Only the determination of low molecular-weight substances, such as therapeutic agents, drugs of abuse and hormones is considered because the measured change in fluorescence polarization depends on the molecular size of the analyte.
M C, Gutierrez +2 more
openaire +2 more sources
Platelet activation studied by fluorescence polarization
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1984Platelet activation was elevated by changes in the fluorescence anisotropy of the sulfhydryl-reactive fluorescent probe, (5-[2-(iodoacetyl) aminacetyl]aminonaphthalene-1-sulfonic acid. The membrane-permeable fluorophore was shown to bind to a multitude of cytoplasmic and membrane proteins.
M, Steiner, E F, Lüscher
openaire +2 more sources
Polarization of molecular x-ray fluorescence
Physical Review Letters, 1988Polarization of Cl K\ensuremath{\beta} x-ray fluorescence following selective excitation of gaseous ${\mathrm{CH}}_{3}$CL with synchrotron radiation is reported. The degree of polarization of the fluorescence depends sensitively on the chosen incident excitation energy in the Cl K-edge region.
, Lindle +8 more
openaire +2 more sources
Fluorescence polarization in immunochemistry
Immunochemistry, 1970W B, Dandliker, V A, De Saussure
openaire +3 more sources