Results 21 to 30 of about 93,742 (266)

Characterization of the Interactions between Minocycline Hydrochloride and Trypsin with Spectroscopic and Molecular Docking Technology

Molecules, 2023
In the current study, the interaction of minocycline hydrochloride (MC) and trypsin (TRP) was studied using fluorescence spectroscopy, synchronous fluorescence spectroscopy, three-dimensional fluorescence spectroscopy, UV-Vis spectroscopy, and molecular ...
Xiaoxia Wang, Jisheng Sun, Litong Ma, Zhihua Nie, Huazheng Sai, Jianguo Cheng, Jianguo Duan   +6 more
doaj   +1 more source

New Fluorescence Quenching Approach for Determination of Valsartan in Certain Tablets and Spiked Biological Fluids

ARO-The Scientific Journal of Koya University, 2020
A new, simple, selective, sensitive, fast, economical, and reliable fluorescence quenching method for the quantitation of valsartan was investigated using basic fuchsin act as a fluorometric dye.
Layth I. Abd Ali
doaj   +1 more source

Anthracene Fluorescence Quenching by a Tetrakis (Ketocarboxamide) Cavitand

Journal of Spectroscopy, 2014
Quenching of both fluorescence lifetime and fluorescence intensity of anthracene was investigated in the presence of a newly derived tetrakis (ketocarboxamide) cavitand at various concentrations.
Tibor Zoltan Janosi, Jouko Korppi-Tommola, Zsolt Csok, Laszlo Kollar, Pasi Myllyperkio, Janos Erostyak   +5 more
doaj   +1 more source

Fluorescence quenching by methylcytosine-metal complexation [PDF]

Nucleic Acids Symposium Series, 2006
We report the control of fluorescence emission from the fluorophore fixed on DNA using the methylcytosine-selective addition of an osmium(VI)-bipyridine complex. We synthesized the DNA modified by a microenvironment-sensitive fluorophore, 2-dimethylamino-6-acylnaphthalene.
Kazuo, Tanaka, Kazuki, Tainaka, Akimitsu, Okamoto   +2 more
openaire   +2 more sources

Insight into the Interaction between the HIV-1 Integrase Inhibitor Elvitegravir and Bovine Serum Albumin: A Spectroscopic Study

Journal of Spectroscopy, 2015
The interaction between the anti-HIV drug Elvitegravir (EVG) and bovine serum albumin (BSA) was investigated by fluorescence spectroscopy and UV-visible absorption spectra. The mechanism for quenching the fluorescence of BSA by EVG is discussed.
Ali Saber Abdelhameed
doaj   +1 more source

Synthesis of 5-Dialkyl(aryl)aminomethyl-8-hydroxyquinoline Dansylates as Selective Fluorescent Sensors for Fe3+

Molecules, 2007
A series of 5-dialkyl(aryl)aminomethyl-8-hydroxyquinoline dansylates were synthesized and their fluoroionophoric properties toward representative alkali ions, alkaline earth ions and transition metal ions were investigated.
Yaowu Sha, Feng Wang, Ruogu Peng
doaj   +1 more source

Tryptophan Fluorescence Quenching Assays for Measuring Protein-ligand Binding Affinities: Principles and a Practical Guide

Bio-Protocol, 2019
Tryptophan fluorescence quenching is a type of fluorescence spectroscopy used for binding assays. The assay relies on the ability to quench the intrinsic fluorescence of tryptophan residues within a protein that results from changes in the local ...
Anthony Yammine, Jinlong Gao, Ann Kwan
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Fluorescence Quenching of Aromatic Amino Acids by Rhodium Nanoparticles

Substantia
In this paper, the fluorescence quenching of the aromatic amino acids tyrosine and tryptophan by rhodium nanoparticles has been investigated.The choice of rhodium nanoparticles was determined by the fact that the plasmonic maximum of the nanoparticles ...
Elizaveta Demishkevich, Alexander Zozulya, Andrey Zyubin, Ivan Lyatun, Ilia Samusev   +4 more
doaj   +1 more source