Results 241 to 250 of about 41,336 (313)

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner   +6 more
wiley   +1 more source

All-optical strategies to minimize photobleaching in reversibly switchable fluorescent proteins. [PDF]

open access: yesNat Commun
Marín-Aguilera G   +8 more
europepmc   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara   +3 more
wiley   +1 more source

pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive

open access: yesAdvanced Functional Materials, Volume 36, Issue 10, 2 February 2026.
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy   +5 more
wiley   +1 more source

Nanomaterial‐Integrated Fiber Neural Probes for Deep Brain Monitoring and Modulation: Challenges and Opportunities

open access: yesAdvanced Functional Materials, Volume 36, Issue 11, 5 February 2026.
The article presents nanomaterial‐integrated fiber neural probes as innovative tools for deep brain molecular sensing, neural stimulation, and temperature monitoring. It examines breakthroughs in SERS‐based biomolecule detection, thermoplasmonic activation, and luminescent thermometry, alongside strategies to overcome stability, specificity, and ...
Di Zheng   +5 more
wiley   +1 more source

Liquid‐in‐Liquid Prints: High‐Density Biochemically Encoded Information Preserved in Microdroplet Arrays

open access: yesAdvanced Materials, Volume 38, Issue 7, 2 February 2026.
This work introduces a novel approach for encoding and storing information in the liquid state in microdroplet arrays. These liquid‐in‐liquid prints are generated by a droplet printing system capable of dynamically setting the composition of each droplet pixel.
Maximilian Breitfeld   +5 more
wiley   +1 more source

Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications

open access: yesAggregate, Volume 7, Issue 2, February 2026.
The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed   +3 more
wiley   +1 more source

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