Results 41 to 50 of about 206,440 (289)

Amine molecular cages as supramolecular fluorescent explosive sensors: a computational perspective [PDF]

, 2016
We investigate using a computational approach the physical and chemical processes underlying the application of organic (macro)molecules as fluorescence quenching sensors for explosives sensing. We concentrate on the use of amine molecular cages to sense
Berardo, E, Jelfs, KE, Peveler, WJ, Zwijnenburg, MA   +3 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism

Nature Communications, 2019
AMP-activated protein kinase AMPK senses and regulates cellular energy state. Here the authors engineer a synthetic sensor, AMPfret, that allows direct, real-time readout of the AMPK conformational state by fluorescence resonance energy transfer (FRET).
Martin Pelosse, Cécile Cottet-Rousselle, Cécile M. Bidan, Aurélie Dupont, Kapil Gupta, Imre Berger, Uwe Schlattner   +6 more
doaj   +1 more source

Fluorescence resonance energy transfer sensors for quantitative monitoring of pentose and disaccharide accumulation in bacteria

Biotechnology for Biofuels, 2008
Background Engineering microorganisms to improve metabolite flux requires detailed knowledge of the concentrations and flux rates of metabolites and metabolic intermediates in vivo.
Looger Loren L, Lager Ida, Kaper Thijs, Chermak Diane, Frommer Wolf B   +4 more
doaj   +1 more source

Time-resolved FRET fluorescence spectroscopy of visible fluorescent protein pairs [PDF]

, 2010
Förster resonance energy transfer (FRET) is a powerful method for obtaining information about small-scale lengths between biomacromolecules. Visible fluorescent proteins (VFPs) are widely used as spectrally different FRET pairs, where one VFP acts as a ...
Birch, D.J.S., Borst, J.W., Brochon, J.C., Hoek, A., van, Laptenok, S., Visser, A.J.W.G., Visser, N.V.   +6 more
core   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

White Light Emission by Simultaneous One Pot Encapsulation of Dyes into One-Dimensional Channelled Aluminophosphate

Nanomaterials, 2020
By simultaneous occlusion of rationally chosen dyes, emitting in the blue, green and red region of the electromagnetic spectrum, into the one-dimensional channels of a magnesium-aluminophosphate with AEL-zeolitic type structure, MgAPO-11, a solid-state ...
Rebeca Sola-Llano, Ainhoa Oliden-Sánchez, Almudena Alfayate, Luis Gómez-Hortigüela, Joaquín Pérez-Pariente, Teresa Arbeloa, Johan Hofkens, Eduard Fron, Virginia Martínez-Martínez   +8 more
doaj   +1 more source

Fluorescence Resonance Energy Transfer in Polydiacetylene Liposomes [PDF]

The Journal of Physical Chemistry B, 2008
Conjugated polydiacetylene (PDA) possessing stimuli-responsive properties has been intensively investigated for developing efficient sensors. We report here fluorescence resonance energy transfer (FRET) in liposomes synthesized using different molar ratios of dansyl-tagged diacetylene and diacetylene-carboxylic acid monomers.
Xuelian, Li, Shelton, Matthews, Punit, Kohli   +2 more
openaire   +2 more sources

Probing Plasmons in Graphene by Resonance Energy Transfer

, 2011
We propose a novel method to probe electronic excitations in graphene by monitoring the fluorescence quenching of a semiconductor quantum dot (or a dye molecule) due to the resonance energy transfer to the graphene sheet.
Efimov, Anatoly, Velizhanin, Kirill A.
core   +1 more source